PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7873450-9 1995 This increase in TGF-beta activity by DHEA-sulfate was both time- and dose-dependent, and was not blocked by cotreatment with the specific aromatase inhibitor 4-hydroxyandrostenedione (1 microM). Dehydroepiandrosterone Sulfate 38-50 transforming growth factor beta 1 Homo sapiens 17-25 7873450-10 1995 Immunoprecipitations of the hOB cell conditioned-media with isoform-specific TGF-beta neutralizing-antibodies indicated that TGF-beta 2 was predominantly produced by the cells in response to DHEA-sulfate treatment. Dehydroepiandrosterone Sulfate 191-203 transforming growth factor beta 1 Homo sapiens 77-85 7895901-6 1994 In contrast, TGF beta 1 alone or together with ACTH decreased DHAS secretion, but not cortisol secretion. Dehydroepiandrosterone Sulfate 62-66 transforming growth factor beta 1 Homo sapiens 13-23 7962271-6 1994 Whatever the experimental condition, TGF beta 1 did not reduce basal or ACTH-stimulated cortisol production, but the production of dehydroepiandrosterone sulfate of TGF beta 1-treated cells was always decreased. Dehydroepiandrosterone Sulfate 131-161 transforming growth factor beta 1 Homo sapiens 165-175 7962271-7 1994 The effects of TGF beta 1 on 3 beta-hydroxysteroid dehydrogenase mRNA and dehydroepiandrosterone sulfate were opposite the change observed at the time of adrenarche. Dehydroepiandrosterone Sulfate 74-104 transforming growth factor beta 1 Homo sapiens 15-25 8206321-3 1994 Inhibition of basal dehydroepiandrosterone sulfate (DS) production usually was noted only after 3 or more days of treatment with > or = 0.1 ng TGF-beta/ml. Dehydroepiandrosterone Sulfate 20-50 transforming growth factor beta 1 Homo sapiens 146-154 8206321-3 1994 Inhibition of basal dehydroepiandrosterone sulfate (DS) production usually was noted only after 3 or more days of treatment with > or = 0.1 ng TGF-beta/ml. Dehydroepiandrosterone Sulfate 52-54 transforming growth factor beta 1 Homo sapiens 146-154 8206321-7 1994 These results are suggestive that TGF-beta differentially inhibits DS and cortisol production by human fetal adrenal cells and that the site of TGF-beta action on steroidogenesis may be distal to the generation of cAMP. Dehydroepiandrosterone Sulfate 67-69 transforming growth factor beta 1 Homo sapiens 34-42