PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21752346-6 2011 Dehydroepiandrosterone sulfate showed a significant correlation with peak Vo2 (r = 0.29, p = 0.007), predicted peak Vo2 (r = 0.28, p = 0.006), and VE/Vco2 slope (r = -0.39, p <0.001), whereas total testosterone, estimated free testosterone, and insulin-like growth factor-1 were not significantly correlated. Dehydroepiandrosterone Sulfate 0-30 insulin like growth factor 1 Homo sapiens 248-276 11408725-0 2001 Plasma insulin-like growth factor I levels in the elderly: relation to plasma dehydroepiandrosterone sulfate levels, nutritional status, health and mortality. Dehydroepiandrosterone Sulfate 78-108 insulin like growth factor 1 Homo sapiens 7-35 22286784-15 2011 The stepwise multiple regression revealed DHEAS and LH as predictors of IGF-I level in group A, while in group B none of the parameters predicted IGF-I level. Dehydroepiandrosterone Sulfate 42-47 insulin like growth factor 1 Homo sapiens 72-77 17381481-0 2007 Independent association between insulin-like growth factor-I and dehydroepiandrosterone sulphate in women in middle adulthood. Dehydroepiandrosterone Sulfate 65-96 insulin like growth factor 1 Homo sapiens 32-60 11408725-2 2001 Because plasma IGF-I levels have been reported to be enhanced by dehydroepiandrosterone (DHEA) administration, it has been suggested that the IGF-I may be implicated in some of the reported associations between low DHEA sulfate (DHEAS) levels and impaired health measures in elderly subjects. Dehydroepiandrosterone Sulfate 215-227 insulin like growth factor 1 Homo sapiens 142-147 10821876-1 2000 Data from animal and in vitro studies suggest that the growth-promoting effects of the adrenal androgen dehydroepiandrosterone sulfate (DHEAS) may be mediated by stimulation of insulin-like growth factor-I (IGF-I) and/or inhibition of interleukin 6 (IL-6), a cytokine mediator of bone resorption. Dehydroepiandrosterone Sulfate 104-134 insulin like growth factor 1 Homo sapiens 177-205 11314741-0 2001 Relationships between cortisol, dehydroepiandrosterone sulphate and insulin-like growth factor-I system in dementia. Dehydroepiandrosterone Sulfate 32-63 insulin like growth factor 1 Homo sapiens 68-96 11847477-9 2001 On the combination of 15 mg/m2 DHEAS and full estrogen substitution, IGF-I SDS increased to an average of -0.15. Dehydroepiandrosterone Sulfate 31-36 insulin like growth factor 1 Homo sapiens 69-74 11082899-1 2000 OBJECTIVES: The serum concentration of dehydroepiandrosterone sulfate (DHEAS) in relation to serum levels of follicle stimulating hormone, estradiol, insulin-like growth factor I (IGF-I) and height and weight velocity in girls during puberty were studied. Dehydroepiandrosterone Sulfate 39-69 insulin like growth factor 1 Homo sapiens 150-178 11082899-1 2000 OBJECTIVES: The serum concentration of dehydroepiandrosterone sulfate (DHEAS) in relation to serum levels of follicle stimulating hormone, estradiol, insulin-like growth factor I (IGF-I) and height and weight velocity in girls during puberty were studied. Dehydroepiandrosterone Sulfate 39-69 insulin like growth factor 1 Homo sapiens 180-185 10821876-1 2000 Data from animal and in vitro studies suggest that the growth-promoting effects of the adrenal androgen dehydroepiandrosterone sulfate (DHEAS) may be mediated by stimulation of insulin-like growth factor-I (IGF-I) and/or inhibition of interleukin 6 (IL-6), a cytokine mediator of bone resorption. Dehydroepiandrosterone Sulfate 104-134 insulin like growth factor 1 Homo sapiens 207-212 10411234-9 1999 In OB women, IGF-I concentrations positively correlated with PRL (r = 0.31), testosterone (r = 0.30), androstenedione (r = 0.30), and dehydroepiandrosterone-sulfate (DHEAS) concentrations (r = 0.41). Dehydroepiandrosterone Sulfate 134-164 insulin like growth factor 1 Homo sapiens 13-18 10487697-0 1999 Dehydroepiandrosterone sulfate enhances natural killer cell cytotoxicity in humans via locally generated immunoreactive insulin-like growth factor I. Dehydroepiandrosterone Sulfate 0-30 insulin like growth factor 1 Homo sapiens 120-148 10487697-1 1999 Experimental and clinical investigations suggest the hypothesis that dehydroepiandrosterone sulfate (DHEAS) can positively influence natural killer (NK) immunity via locally produced insulin-like growth factor I (IGF-I) from NK cells. Dehydroepiandrosterone Sulfate 69-99 insulin like growth factor 1 Homo sapiens 183-211 10487697-1 1999 Experimental and clinical investigations suggest the hypothesis that dehydroepiandrosterone sulfate (DHEAS) can positively influence natural killer (NK) immunity via locally produced insulin-like growth factor I (IGF-I) from NK cells. Dehydroepiandrosterone Sulfate 69-99 insulin like growth factor 1 Homo sapiens 213-218 10411234-9 1999 In OB women, IGF-I concentrations positively correlated with PRL (r = 0.31), testosterone (r = 0.30), androstenedione (r = 0.30), and dehydroepiandrosterone-sulfate (DHEAS) concentrations (r = 0.41). Dehydroepiandrosterone Sulfate 166-171 insulin like growth factor 1 Homo sapiens 13-18 7674231-5 1995 A statistically significant correlation was observed between changes of IGF-I levels and of dehydroepiandrosterone sulphate (DHEAS). Dehydroepiandrosterone Sulfate 92-123 insulin like growth factor 1 Homo sapiens 72-77 10099969-5 1999 Serum IGF-I was only correlated with basal dehydroepiandrosterone sulphate (DHEA-S), while insulin exhibited a strong correlation with the delta 4 pathway and androstenedione formation in particular. Dehydroepiandrosterone Sulfate 43-74 insulin like growth factor 1 Homo sapiens 6-11 10099969-5 1999 Serum IGF-I was only correlated with basal dehydroepiandrosterone sulphate (DHEA-S), while insulin exhibited a strong correlation with the delta 4 pathway and androstenedione formation in particular. Dehydroepiandrosterone Sulfate 76-82 insulin like growth factor 1 Homo sapiens 6-11 10408670-7 1998 RESULTS: In women, DHEAS correlated with VO2max (partial correlation: r=0.33; P=0.05), MHDEE (r=0.50; P=0.002), DEE > 3 METs (r=0.49; P=0.003) and sport activity (r=0.35; P=0.04) whereas IGF-I correlated with MHDEE (r=0.48; P=0.004). Dehydroepiandrosterone Sulfate 19-24 insulin like growth factor 1 Homo sapiens 190-195 10408670-8 1998 DHEAS was correlated with IGF-I (r=0.43; P < 0.02) and with testosterone (r=0.41; P < 0.02). Dehydroepiandrosterone Sulfate 0-5 insulin like growth factor 1 Homo sapiens 26-31 9250451-5 1997 Using multiple regression analysis, HbA1c, insulin dose, and DHEAS were significantly correlated to IGF-I SD score (R2 = 0.253, P = 0.001). Dehydroepiandrosterone Sulfate 61-66 insulin like growth factor 1 Homo sapiens 100-105 10727032-0 1999 Dehydroepiandrosterone-sulfate (DHEA-S) restores the release of IGF-I from natural killer (NK) immune in old patients with dementia of Alzheimer"s type (DAT). Dehydroepiandrosterone Sulfate 0-30 insulin like growth factor 1 Homo sapiens 64-69 10727032-0 1999 Dehydroepiandrosterone-sulfate (DHEA-S) restores the release of IGF-I from natural killer (NK) immune in old patients with dementia of Alzheimer"s type (DAT). Dehydroepiandrosterone Sulfate 32-38 insulin like growth factor 1 Homo sapiens 64-69 7674231-5 1995 A statistically significant correlation was observed between changes of IGF-I levels and of dehydroepiandrosterone sulphate (DHEAS). Dehydroepiandrosterone Sulfate 125-130 insulin like growth factor 1 Homo sapiens 72-77 7515387-14 1994 In conclusion, restoring DHEA and DS to young adult levels in men and women of advancing age induced an increase in the bioavailability of IGF-I, as reflected by an increase in IGF-I and a decrease in IGFBP-1 levels. Dehydroepiandrosterone Sulfate 34-36 insulin like growth factor 1 Homo sapiens 139-144 7515387-14 1994 In conclusion, restoring DHEA and DS to young adult levels in men and women of advancing age induced an increase in the bioavailability of IGF-I, as reflected by an increase in IGF-I and a decrease in IGFBP-1 levels. Dehydroepiandrosterone Sulfate 34-36 insulin like growth factor 1 Homo sapiens 177-182 2138277-9 1990 In prepubertal patients, somatomedin C/IGFI was slightly but highly significantly correlated to the growth hormone sleep secretion (r = 0.27, p less than 0.001) and to dehydroepiandrosterone sulfate (r = 0.36, p less than 0.001), but growth hormone and dehydroepiandrosterone sulfate were not correlated together. Dehydroepiandrosterone Sulfate 168-198 insulin like growth factor 1 Homo sapiens 25-38 8401752-2 1993 The present study was undertaken to evaluate the possibility of a relationship between the circulating levels of IGF-1 and those of dehydroepiandrosterone sulphate (DHEAS) in 25 fertile obese women. Dehydroepiandrosterone Sulfate 132-163 insulin like growth factor 1 Homo sapiens 113-118 1838953-4 1991 IGF-I concentration was higher in cysts with a Na+/K+ ratio greater than 3 (greater than 3) and was inversely related to both dehydroepiandrosterone sulfate (DHEA-S) and epidermal growth factor (EGF) concentration (p less than 0.001). Dehydroepiandrosterone Sulfate 126-156 insulin like growth factor 1 Homo sapiens 0-5 1838953-4 1991 IGF-I concentration was higher in cysts with a Na+/K+ ratio greater than 3 (greater than 3) and was inversely related to both dehydroepiandrosterone sulfate (DHEA-S) and epidermal growth factor (EGF) concentration (p less than 0.001). Dehydroepiandrosterone Sulfate 158-164 insulin like growth factor 1 Homo sapiens 0-5 2142388-9 1990 In prepubertal patients, somatomedin C/IGF I was slightly but highly significantly correlated to growth hormone sleep secretion (r = 0.27, p less than 0.001) and to dehydroepiandrosterone sulfate (r = 0.36, p less than 0.001), but growth hormone and dehydroepiandrosterone sulfate were not correlated with each other. Dehydroepiandrosterone Sulfate 165-195 insulin like growth factor 1 Homo sapiens 25-38 2142388-9 1990 In prepubertal patients, somatomedin C/IGF I was slightly but highly significantly correlated to growth hormone sleep secretion (r = 0.27, p less than 0.001) and to dehydroepiandrosterone sulfate (r = 0.36, p less than 0.001), but growth hormone and dehydroepiandrosterone sulfate were not correlated with each other. Dehydroepiandrosterone Sulfate 165-195 insulin like growth factor 1 Homo sapiens 39-44 2142388-9 1990 In prepubertal patients, somatomedin C/IGF I was slightly but highly significantly correlated to growth hormone sleep secretion (r = 0.27, p less than 0.001) and to dehydroepiandrosterone sulfate (r = 0.36, p less than 0.001), but growth hormone and dehydroepiandrosterone sulfate were not correlated with each other. Dehydroepiandrosterone Sulfate 250-280 insulin like growth factor 1 Homo sapiens 25-38 2142388-9 1990 In prepubertal patients, somatomedin C/IGF I was slightly but highly significantly correlated to growth hormone sleep secretion (r = 0.27, p less than 0.001) and to dehydroepiandrosterone sulfate (r = 0.36, p less than 0.001), but growth hormone and dehydroepiandrosterone sulfate were not correlated with each other. Dehydroepiandrosterone Sulfate 250-280 insulin like growth factor 1 Homo sapiens 39-44 2138277-9 1990 In prepubertal patients, somatomedin C/IGFI was slightly but highly significantly correlated to the growth hormone sleep secretion (r = 0.27, p less than 0.001) and to dehydroepiandrosterone sulfate (r = 0.36, p less than 0.001), but growth hormone and dehydroepiandrosterone sulfate were not correlated together. Dehydroepiandrosterone Sulfate 168-198 insulin like growth factor 1 Homo sapiens 39-43 2138277-9 1990 In prepubertal patients, somatomedin C/IGFI was slightly but highly significantly correlated to the growth hormone sleep secretion (r = 0.27, p less than 0.001) and to dehydroepiandrosterone sulfate (r = 0.36, p less than 0.001), but growth hormone and dehydroepiandrosterone sulfate were not correlated together. Dehydroepiandrosterone Sulfate 253-283 insulin like growth factor 1 Homo sapiens 25-38 2138277-9 1990 In prepubertal patients, somatomedin C/IGFI was slightly but highly significantly correlated to the growth hormone sleep secretion (r = 0.27, p less than 0.001) and to dehydroepiandrosterone sulfate (r = 0.36, p less than 0.001), but growth hormone and dehydroepiandrosterone sulfate were not correlated together. Dehydroepiandrosterone Sulfate 253-283 insulin like growth factor 1 Homo sapiens 39-43 3264254-5 1988 Time-course studies indicated that the effects were detectable at 12 h, and continued to increase up to 48 h. The conversion of added dehydroepiandrosterone sulfate (DHEAS) to E2 was stimulated by CT and TPA and inhibited by IGF-I in a concentration-dependent manner. Dehydroepiandrosterone Sulfate 166-171 insulin like growth factor 1 Homo sapiens 225-230 2523898-1 1989 The relationships between plasma insulin, insulin-like growth factor I (IGF-I) and dehydroepiandrosterone sulfate (DHEAS) concentrations in normal subjects have not been defined. Dehydroepiandrosterone Sulfate 83-113 insulin like growth factor 1 Homo sapiens 42-70 2523898-1 1989 The relationships between plasma insulin, insulin-like growth factor I (IGF-I) and dehydroepiandrosterone sulfate (DHEAS) concentrations in normal subjects have not been defined. Dehydroepiandrosterone Sulfate 83-113 insulin like growth factor 1 Homo sapiens 72-77 3264254-5 1988 Time-course studies indicated that the effects were detectable at 12 h, and continued to increase up to 48 h. The conversion of added dehydroepiandrosterone sulfate (DHEAS) to E2 was stimulated by CT and TPA and inhibited by IGF-I in a concentration-dependent manner. Dehydroepiandrosterone Sulfate 134-164 insulin like growth factor 1 Homo sapiens 225-230 2953635-6 1987 SmC/IGF 1 increased both LH/hCG binding (4.3-fold), basal testosterone (4-fold) and DHAS- and hCG-stimulated testosterone and DHAS (dehydroepiandrosterone sulfate) production (15.5- and 6.4-fold respectively). Dehydroepiandrosterone Sulfate 84-88 insulin like growth factor 1 Homo sapiens 4-9 2953635-6 1987 SmC/IGF 1 increased both LH/hCG binding (4.3-fold), basal testosterone (4-fold) and DHAS- and hCG-stimulated testosterone and DHAS (dehydroepiandrosterone sulfate) production (15.5- and 6.4-fold respectively). Dehydroepiandrosterone Sulfate 126-130 insulin like growth factor 1 Homo sapiens 4-9 2953635-6 1987 SmC/IGF 1 increased both LH/hCG binding (4.3-fold), basal testosterone (4-fold) and DHAS- and hCG-stimulated testosterone and DHAS (dehydroepiandrosterone sulfate) production (15.5- and 6.4-fold respectively). Dehydroepiandrosterone Sulfate 132-162 insulin like growth factor 1 Homo sapiens 4-9 2993344-9 1985 The recovery of somatomedin-C before the recovery of adrenal androgens, however, and the positive correlation between plasma somatomedin-C and the integrated level of plasma DHAS (r = 0.50; P less than 0.02) are consistent with the hypothesis that somatomedin-C is a stimulus for adrenal androgen secretion. Dehydroepiandrosterone Sulfate 174-178 insulin like growth factor 1 Homo sapiens 125-138 2993344-9 1985 The recovery of somatomedin-C before the recovery of adrenal androgens, however, and the positive correlation between plasma somatomedin-C and the integrated level of plasma DHAS (r = 0.50; P less than 0.02) are consistent with the hypothesis that somatomedin-C is a stimulus for adrenal androgen secretion. Dehydroepiandrosterone Sulfate 174-178 insulin like growth factor 1 Homo sapiens 125-138