PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15196791-7	2004	These results showed that DHEAS prevented the development of morphine tolerance and dependence and suggested that the attenuating effects of DHEAS might result from the regulation of c-fos mRNA expression, which is possibly involved the signaling activation of ERK, but not of cAMP pathway.	Dehydroepiandrosterone Sulfate	141-146	FBJ osteosarcoma oncogene	Mus musculus	183-188	
15196791-0	2004	A neuroactive steroid, dehydroepiandrosterone sulfate, prevents the development of morphine dependence and tolerance via c-fos expression linked to the extracellular signal-regulated protein kinase.	Dehydroepiandrosterone Sulfate	23-53	FBJ osteosarcoma oncogene	Mus musculus	121-126	
15196791-4	2004	The expression of c-fos mRNA was observed in the frontal cortex and thalamus of mice showing signs of naloxone-precipitated withdrawal, while the expression of c-fos mRNA was significantly diminished by co-administration of DHEAS with morphine.	Dehydroepiandrosterone Sulfate	224-229	FBJ osteosarcoma oncogene	Mus musculus	18-23	
15196791-4	2004	The expression of c-fos mRNA was observed in the frontal cortex and thalamus of mice showing signs of naloxone-precipitated withdrawal, while the expression of c-fos mRNA was significantly diminished by co-administration of DHEAS with morphine.	Dehydroepiandrosterone Sulfate	224-229	FBJ osteosarcoma oncogene	Mus musculus	160-165	
15196791-7	2004	These results showed that DHEAS prevented the development of morphine tolerance and dependence and suggested that the attenuating effects of DHEAS might result from the regulation of c-fos mRNA expression, which is possibly involved the signaling activation of ERK, but not of cAMP pathway.	Dehydroepiandrosterone Sulfate	26-31	FBJ osteosarcoma oncogene	Mus musculus	183-188