PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9716151-9 1998 Contrast agents inhibited binding of thrombin to fibrin, with ionic agents producing a more potent effect than ioversol (p <0.02). ioversol 111-119 coagulation factor II, thrombin Homo sapiens 37-45 7738783-2 1995 All contrast media, including ionic (iothalamate and ioxaglate) and non-ionic ones (iohexol, ioversol and iopamidol), suppressed the collagen- and thrombin-induced aggregation in a concentration-dependent manner. ioversol 93-101 coagulation factor II, thrombin Homo sapiens 147-155 2296655-5 1990 The authors conclude that this difference presents a novel hazard in that iopamidol, iohexol, and ioversol permit thrombin generation to occur while inhibiting the fibrin polymerization step of blood coagulation, thus posing a significant, albeit theoretical, threat to patient well-being. ioversol 98-106 coagulation factor II, thrombin Homo sapiens 114-122