PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26969380-6	2016	Immunoblotting and real time polymerase chain reaction (RT-PCR) analysis showed that sinapine downregulated multi-drug resistance 1 (MDR1) expression.	sinapine	85-93	ATP binding cassette subfamily B member 1	Homo sapiens	108-131	
26969380-6	2016	Immunoblotting and real time polymerase chain reaction (RT-PCR) analysis showed that sinapine downregulated multi-drug resistance 1 (MDR1) expression.	sinapine	85-93	ATP binding cassette subfamily B member 1	Homo sapiens	133-137	
26969380-8	2016	Chromatin immunoprecipitation (ChIP) assay indicated that sinapine inhibited binding of the transcription factor NF-kappaB to the MDR1 promoter.	sinapine	58-66	ATP binding cassette subfamily B member 1	Homo sapiens	130-134	
26969380-9	2016	CONCLUSIONS: Our findings indicated that sinapine played an important role in the downregulation of MDR1 expression through suppression of fibroblast growth factor receptor (FGFR)4/FRS2alpha-ERK1/2 mediated NF-kappaB activation in MCF-7/dox cancer cells.	sinapine	41-49	ATP binding cassette subfamily B member 1	Homo sapiens	100-104	
24607798-0	2014	Sinapine as an active compound for inhibiting the proliferation of Caco-2 cells via downregulation of P-glycoprotein.	sinapine	0-8	ATP binding cassette subfamily B member 1	Homo sapiens	102-116	
24607798-8	2014	Immunoblotting and QT-PCR analysis showed that sinapine suppressed P-glycoprotein (P-gp) expression via ubiquitination.	sinapine	47-55	ATP binding cassette subfamily B member 1	Homo sapiens	67-81	
24607798-8	2014	Immunoblotting and QT-PCR analysis showed that sinapine suppressed P-glycoprotein (P-gp) expression via ubiquitination.	sinapine	47-55	ATP binding cassette subfamily B member 1	Homo sapiens	83-87	
24607798-10	2014	These results indicated that sinapine played an important role in the down-regulation of P-gp expression through suppression of FGFR4-FRS2alpha-ERK1/2 signaling pathway.	sinapine	29-37	ATP binding cassette subfamily B member 1	Homo sapiens	89-93