PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32898626-10 2021 Screening experiments using recombinant rat cytochrome P450 (CYP) isoforms showed that CYP1A1, CYP2C6, CYP2C11, CYP2D1, and CYP3A2 were involved in GM metabolism. geissoschizine methylether 148-150 cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus 103-110 32898626-11 2021 Of these CYP isoforms, the use of anti-rat CYP antibodies indicated that male-dependent CYP2C11 and CYP3A2 were predominantly involved in the liver microsomal GM metabolism with gender differences. geissoschizine methylether 159-161 cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus 88-95 32898626-12 2021 CONCLUSIONS: These results suggest that the cause of gender differences in plasma GM pharmacokinetics in rats is most likely because of male-dependent CYP2C11 and CYP3A2, and provide also useful information to further evaluate the pharmacological and toxicological effects in future. geissoschizine methylether 82-84 cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus 151-158