PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19592534-5 2009 Overexpression of the hydroxymethylglutaryl-coenzyme A reductase (HMG1) gene, which encodes the major rate-limiting enzyme of the mevalonate pathway, resulted in overproduction of squalene (191.9 mg liter(-1)) rather than GGOH (0.2 mg liter(-1)) in test tube cultures. ggoh 222-226 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1 Saccharomyces cerevisiae S288C 66-70 19592534-6 2009 Coexpression of the BTS1-DPP1 fusion gene along with the HMG1 gene partially redirected the metabolic flux from squalene to GGOH. ggoh 124-128 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1 Saccharomyces cerevisiae S288C 57-61