PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31185411-3	2019	Following our previous work related to the modification of the hydrogen bond network between alpha-GalCer and CD1d, we have now focused our attention on the synthesis of 3-deoxy-3,3-difluoro- and 3,4-dideoxy-3,3,4,4-tetrafluoro-alpha-GalCer analogues, and studied their ability to stimulate human iNKT cells.	Hydrogen	63-71	CD1d molecule	Homo sapiens	110-114	
31097998-3	2019	The biased activity of ligands could be caused by the hydrogen-bonding interaction between ligands and CD1d according to the Th2-selective cytokine secretion and molecular docking studies.	Hydrogen	54-62	CD1d molecule	Homo sapiens	103-107	
29863807-5	2018	Importantly, the truncated acyl chain containing variants still retain their binding affinities and agonistic activities, which can be associated with an "anchoring effect," that is, formation of a buried hydrogen bond between a polar group on the acyl chain and the CD1d lipid-binding pocket.	Hydrogen	205-213	CD1d molecule	Homo sapiens	267-271	
24900836-2	2014	Although most of the residues in the CD1d binding groove are hydrophobic, some of the amino acids can form hydrogen bonds.	Hydrogen	107-115	CD1d molecule	Homo sapiens	37-41	
31097989-2	2019	To selectively induce the secretion of certain cytokines via introducing hydrogen-bonding interaction with polar amino acid residues in the binding pocket of CD1d, a series of alpha-GalCer analogues with diether moiety in the acyl chain were designed and synthesized.	Hydrogen	73-81	CD1d molecule	Homo sapiens	158-162	
25256626-3	2014	Highly selective 1,2-migration referring to the two substituents R(3) and R(4) (R(4) =H, alkyl, and aryl group) was observed: (1) In the presence of both H and alkyl groups, 1,2-hydrogen migration is exclusive; (2) in the presence of a methyl group (R(3) ), propyl, isopropyl, 4-methylphenyl, and 4-chlorophenyl groups (R(4) ) migrate exclusively.	Hydrogen	178-186	CD1d molecule	Homo sapiens	236-254