PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34273979-11 2021 Intraperitoneal injection of A8 at 1 mg/kg or synaptamide at 5 mg/kg significantly reduced the acute expression of TNF mRNA in the brain and ameliorated chronic optic tract microgliosis, astrogliosis, and axonal degeneration as well as visual deficit caused by injury in WT but not in GPR110 KO mice. synaptamide 46-57 tumor necrosis factor Mus musculus 115-118 34639071-4 2021 As a result, we found that both N-docosahexaenoylethanolamine (synaptamide) and N-eicosapentaenoylethanolamine (EPEA) prevents an LPS-mediated increase in the proinflammatory cytokines TNF-alpha and IL-6 production in the SIM-A9 microglia culture. synaptamide 32-61 tumor necrosis factor Mus musculus 185-194 34639071-4 2021 As a result, we found that both N-docosahexaenoylethanolamine (synaptamide) and N-eicosapentaenoylethanolamine (EPEA) prevents an LPS-mediated increase in the proinflammatory cytokines TNF-alpha and IL-6 production in the SIM-A9 microglia culture. synaptamide 63-74 tumor necrosis factor Mus musculus 185-194 34639071-5 2021 In an in vivo experiment, synaptamide reversed an increase in LPS-mediated hippocampal TNF-alpha and IL-1beta, but EPEA did not. synaptamide 26-37 tumor necrosis factor Mus musculus 87-96 27809877-9 2016 RESULTS: Synaptamide significantly reduced LPS-induced production of TNF-alpha and NO in cultured microglia cells. synaptamide 9-20 tumor necrosis factor Mus musculus 69-78