PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10783065-0	2000	Molecular dynamics simulations of bovine cathepsin B and its complex with CA074.	N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline	74-79	cathepsin B	Bos taurus	41-52	
10739956-0	2000	Substrate specificity of bovine cathepsin B and its inhibition by CA074, based on crystal structure refinement of the complex.	N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline	66-71	cathepsin B	Bos taurus	32-43	
10739956-1	2000	The crystal structure of the bovine spleen cathepsin B (BSCB)-CA074 complex was refined to R = 0.152 using X-ray diffraction data up to 2.18 A resolution.	N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline	62-67	cathepsin B	Bos taurus	43-54	
9192742-0	1997	Binding mode of CA074, a specific irreversible inhibitor, to bovine cathepsin B as determined by X-ray crystal analysis of the complex.	N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline	16-21	cathepsin B	Bos taurus	68-79	
9192742-1	1997	The binding mode of CA074 [N-(L-3-trans-propylcarbamoyl-oxirane-2-carbonyl)-L-isoleucyl-L-pr oline], a specific irreversible inhibitor, to bovine spleen cathepsin B was elucidated by X-ray crystal structure analysis of the complex at 2.2 A resolution (conventional R=0.185).	N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline	20-25	cathepsin B	Bos taurus	153-164	
9211519-3	1997	CA-074 (0.94 microM) inhibited at least 92% and 80% of proteinolytic activity, respectively, for these species: completely inhibited bovine-spleen cathepsin B activity; but showed only marginal inhibition (4%) of rat-liver cathepsin L activity.	N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline	0-6	cathepsin B	Bos taurus	147-158	
1404397-0	1992	Crystallization and preliminary X-ray study of the cathepsin B complexed with CA074, a selective inhibitor.	N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline	78-83	cathepsin B	Bos taurus	51-62	
1404397-1	1992	Cathepsin B from bovine spleen has been purified and crystallized as a complex with a specific inhibitor CA074 [N-(L-3-trans-propylcarbamoyloxirane-2-carbonyl)-L- isoleucyl-L-proline], using the hanging-drop method.	N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline	105-110	cathepsin B	Bos taurus	0-11