PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12242540-6 2002 However, taking the difference in prevalence of PD and SND into account, and because of the low likelihood ratios of the test, an increase of GH after clonidine increases the pre-test probability for PD by about only 5 %, while an absent response of GH also increases the pre-test probability for SND by about 5 %. Clonidine 151-160 gamma-glutamyl hydrolase Homo sapiens 142-144 9217760-5 1997 METHODS: Clonidine is a centrally active alpha 2-adrenoceptor agonist that raises concentrations of GH in serum in healthy people and those with pure autonomic failure (with peripheral lesions), but not in those with MSA (with a central autonomic deficit). Clonidine 9-18 gamma-glutamyl hydrolase Homo sapiens 100-102 9217760-9 1997 FINDINGS: Clonidine raised serum GH concentrations in patients with idiopathic Parkinson"s disease (median increase 8.98 [IQR 6.6-16.6] mU/L), normal participants (13.2 [7.0-18.6] mU/L), and patients with pure autonomic failure (12.5 [5.6-18.2] mU/L). Clonidine 10-19 gamma-glutamyl hydrolase Homo sapiens 33-35 9217760-11 1997 The GH response to clonidine in idiopathic Parkinson"s disease was significantly different from that in MSA-P (p < 0.0002). Clonidine 19-28 gamma-glutamyl hydrolase Homo sapiens 4-6 9217760-13 1997 INTERPRETATION: The GH responses to clonidine clearly differentiated idiopathic Parkinson"s disease from MSA-C and MSA-P. Clonidine 36-45 gamma-glutamyl hydrolase Homo sapiens 20-22 9217760-15 1997 The clonidine-GH test may provide further insight into central neurotransmitter and alpha 2-adrenoceptor-hypothalamic abnormalities in MSA. Clonidine 4-13 gamma-glutamyl hydrolase Homo sapiens 14-16 8047638-2 1994 Since the central alpha 2 adrenergic agonist clonidine is widely used as a therapeutic agent in GTS, the present study aimed at assessing whether GH release after clonidine, representing central alpha 2-adrenergic receptor sensitivity, was altered in GTS. Clonidine 163-172 gamma-glutamyl hydrolase Homo sapiens 146-148 32034477-0 2020 Clonidine GH stimulation test to differentiate MSA from idiopathic late onset cerebellar ataxia: a prospective, controlled study. Clonidine 0-9 gamma-glutamyl hydrolase Homo sapiens 10-12 1522942-8 1992 GH levels after clonidine were blunted in all subjects but one AD patient, probably due to an age-dependent attenuation frequently observed in subjects over 45 years of age. Clonidine 16-25 gamma-glutamyl hydrolase Homo sapiens 0-2 29956027-0 2018 Prospective study of relevance of 123I-MIBG myocardial scintigraphy and clonidine GH test to distinguish Parkinson"s disease and multiple system atrophy. Clonidine 72-81 gamma-glutamyl hydrolase Homo sapiens 82-84