PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7643129-2	1995	This study evaluates the ability of clonidine and related drugs to regulate expression of the gene for the epinephrine-synthesizing enzyme phenylethanolamine N-methyltransferase (PNMT) in the rat adrenal gland and in bovine adrenal chromaffin cell cultures.	Clonidine	36-45	phenylethanolamine-N-methyltransferase	Rattus norvegicus	139-177	
7643129-6	1995	The effects of clonidine on PNMT mRNA appear to be distinct from and additive with those exerted by nicotine.	Clonidine	15-24	phenylethanolamine-N-methyltransferase	Rattus norvegicus	28-32	
7643129-2	1995	This study evaluates the ability of clonidine and related drugs to regulate expression of the gene for the epinephrine-synthesizing enzyme phenylethanolamine N-methyltransferase (PNMT) in the rat adrenal gland and in bovine adrenal chromaffin cell cultures.	Clonidine	36-45	phenylethanolamine-N-methyltransferase	Rattus norvegicus	179-183	
7643129-3	1995	In vivo, PNMT and tyrosine hydroxylase (TH) mRNA levels increase in rat adrenal medulla after a single injection of clonidine.	Clonidine	116-125	phenylethanolamine-N-methyltransferase	Rattus norvegicus	9-13	
6132343-11	1982	In pithed rats the pressor responses to both methoxamine and clonidine were antagonized by SK & F 64139 suggesting blockade of vascular alpha 1-and alpha 2-adrenoceptors by the PNMT inhibitor.	Clonidine	61-70	phenylethanolamine-N-methyltransferase	Rattus norvegicus	181-185	
7401402-3	1980	Clonidine and hydralazine significantly lowered phenylethanolamine N-methyltransferase (PNMT) activity elevated in the nucleus hypothalamicus posterior (NHP) of SHR to the level of KWR, and both drugs or alpha-methyldopa consistently increased PNMT in the nucleus paraventricularis (NPA).	Clonidine	0-9	phenylethanolamine-N-methyltransferase	Rattus norvegicus	48-86	
7401402-3	1980	Clonidine and hydralazine significantly lowered phenylethanolamine N-methyltransferase (PNMT) activity elevated in the nucleus hypothalamicus posterior (NHP) of SHR to the level of KWR, and both drugs or alpha-methyldopa consistently increased PNMT in the nucleus paraventricularis (NPA).	Clonidine	0-9	phenylethanolamine-N-methyltransferase	Rattus norvegicus	88-92	
7401402-3	1980	Clonidine and hydralazine significantly lowered phenylethanolamine N-methyltransferase (PNMT) activity elevated in the nucleus hypothalamicus posterior (NHP) of SHR to the level of KWR, and both drugs or alpha-methyldopa consistently increased PNMT in the nucleus paraventricularis (NPA).	Clonidine	0-9	phenylethanolamine-N-methyltransferase	Rattus norvegicus	244-248