PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18809522-1 2008 BACKGROUND: We sought to evaluate the effects of clonidine on type-2 cationic amino acid transporter (CAT-2) transcription in endotoxin-activated murine macrophages. Clonidine 49-58 dominant cataract 2 Mus musculus 102-107 18809522-7 2008 The data indicated that clonidine significantly enhanced LPS-induced CAT-2 transcription. Clonidine 24-33 dominant cataract 2 Mus musculus 69-74 18809522-10 2008 CONCLUSION: Clonidine enhances CAT-2 transcription in endotoxin-activated murine macrophages. Clonidine 12-21 dominant cataract 2 Mus musculus 31-36 18809522-6 2008 RESULTS: The CAT-2 mRNA concentration of cell cultures receiving LPS plus clonidine (100 microM) or LPS plus clonidine (1000 microM) were significantly higher than that of the cell cultures receiving LPS alone, whereas the CAT-2 mRNA concentrations of cell cultures receiving LPS plus clonidine (10 microM) was comparable to that of cell cultures receiving LPS alone. Clonidine 74-83 dominant cataract 2 Mus musculus 13-18 18809522-6 2008 RESULTS: The CAT-2 mRNA concentration of cell cultures receiving LPS plus clonidine (100 microM) or LPS plus clonidine (1000 microM) were significantly higher than that of the cell cultures receiving LPS alone, whereas the CAT-2 mRNA concentrations of cell cultures receiving LPS plus clonidine (10 microM) was comparable to that of cell cultures receiving LPS alone. Clonidine 109-118 dominant cataract 2 Mus musculus 13-18 18809522-6 2008 RESULTS: The CAT-2 mRNA concentration of cell cultures receiving LPS plus clonidine (100 microM) or LPS plus clonidine (1000 microM) were significantly higher than that of the cell cultures receiving LPS alone, whereas the CAT-2 mRNA concentrations of cell cultures receiving LPS plus clonidine (10 microM) was comparable to that of cell cultures receiving LPS alone. Clonidine 109-118 dominant cataract 2 Mus musculus 13-18