PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8095374-1 1993 In some blood vessels, the alpha 2-adrenergic agonist clonidine simultaneously activates vasoconstrictive alpha-adrenoceptors on smooth muscle cells and endothelial alpha 2-adrenoceptors mediating release of endothelium-derived relaxing factor (EDRF), with the net vascular response representing a balance between these two counteracting pathways. Clonidine 54-63 alpha hemoglobin stabilizing protein Homo sapiens 245-249 8095374-2 1993 To investigate whether clonidine"s modest constrictor effect in human veins is due to simultaneous release of EDRF, the dorsal hand vein compliance technique was used to measure vascular responses in healthy volunteers. Clonidine 23-32 alpha hemoglobin stabilizing protein Homo sapiens 110-114