PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16318667-3 2005 The aim of the present study was to investigate the effect of clonidine on phospholipase A2 activity in an established in vitro model. Clonidine 62-71 phospholipase A2 group IB Homo sapiens 75-91 16318667-6 2005 RESULTS: A massive increase in phospholipase A2 activity was measured after clonidine exposure leading to final values of 92.5 +/- 3.1 pmol mg protein(-1) min(-1) (4.5-fold higher than control values; P < or = 0.01 vs. control). Clonidine 76-85 phospholipase A2 group IB Homo sapiens 31-47 16318667-8 2005 The Lineweaver-Burk representation suggested an interaction of clonidine with the phospholipase A2-substrate complex as well as the phospholipase A2 molecule. Clonidine 63-72 phospholipase A2 group IB Homo sapiens 82-98