PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30198706-3 2019 The development of in vivo imaging radiotracers for VMAT2 is a story of starting with a well-characterized clinically used drug (tetrabenazine) which had a pharmacologically active metabolite: that metabolite that was in stepwise fashion refined and modified to provide both carbon-11 and fluorine-18 labeled VMAT2 radiotracers that are now used for human PET studies of neurodegenerative and psychiatric diseases. Fluorine-18 289-300 solute carrier family 18 member A2 Homo sapiens 52-57