PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25431646-1 2014 The synthesis of fluorine-18 labeled 3-fluoro-5-[(pyridin-3-yl)ethynyl] benzonitrile ([18F]FPEB) for imaging metabotropic glutamate receptor subtype type 5 (mGluR5) was achieved with a commercial continuous-flow microfluidics device. Fluorine-18 17-28 glutamate receptor, ionotropic, kainate 1 Mus musculus 157-163 20411954-2 2010 In an effort to obtain a fluorine-18 labeled analogue of the mGluR5 PET tracer [(11)C]ABP688, 13 novel ligands based on the core structure of ABP688 were synthesized. Fluorine-18 25-36 glutamate receptor, ionotropic, kainate 1 Mus musculus 61-67 15803497-1 2005 Three metabotropic glutamate receptor subtype 5 (mGluR5) PET tracers have been labeled with either carbon-11 or fluorine-18 and their in vitro and in vivo behavior in rhesus monkey has been characterized. Fluorine-18 112-123 glutamate receptor, ionotropic, kainate 1 Mus musculus 49-55 22822714-1 2012 In the search for an optimal fluorine-18-labeled positron emission tomography (PET) radiotracer for imaging metabotropic glutamate receptor subtype 5 (mGluR5), we have prepared a series of five alpha-fluorinated derivatives based on the ABP688 structural manifold by application of a two-step enolization/NFSI alpha-fluorination method. Fluorine-18 29-40 glutamate receptor, ionotropic, kainate 1 Mus musculus 151-157 22885775-1 2012 PURPOSE: [(18)F]SP203 (3-fluoro-5-(2-(2-([(18)F]fluoromethyl)-thiazol-4-yl)ethynyl)benzonitrile) is an effective high-affinity and selective radioligand for imaging metabotropic 5 receptors (mGluR5) in human brain with PET. Fluorine-18 9-15 glutamate receptor, ionotropic, kainate 1 Mus musculus 191-197 21845279-1 2011 3-Fluoro-1-((thiazol-4-yl)ethynyl)benzenes constitute an important class of high-affinity metabotropic glutamate subtype 5 receptor (mGluR5) ligands, some of which have been labeled with fluorine-18 (t(1/2) = 109.7 min), to provide radioligands for molecular imaging of brain mGluR5 in living animal and human subjects with positron emission tomography (PET). Fluorine-18 187-198 glutamate receptor, ionotropic, kainate 1 Mus musculus 133-139