PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17360805-7 2007 By analysis of downstream signaling, we could provide further evidence that combined activation of PTX-insensitive (Gq-mediated) and PTX-sensitive (Gi-mediated) pathways by cysLT1 may explain the strong and broad effects of cysteinyl-leukotrienes in early hematopoietic cells, while signaling of CXCR4 and S1P1 solely depends on Gi proteins, resulting in effects mainly restricted to migration and adhesion. cysteinyl-leukotriene 224-246 C-X-C motif chemokine receptor 4 Homo sapiens 296-301