PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31365289-3	2019	Here we showed that bilateral microinjection of both orexin-A and orexin-B into the globus pallidus alleviated motor deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonian mice.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	129-173	hypocretin	Mus musculus	53-61	
31365289-3	2019	Here we showed that bilateral microinjection of both orexin-A and orexin-B into the globus pallidus alleviated motor deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonian mice.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	129-173	hypocretin	Mus musculus	66-74	
31365289-3	2019	Here we showed that bilateral microinjection of both orexin-A and orexin-B into the globus pallidus alleviated motor deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonian mice.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	175-179	hypocretin	Mus musculus	53-61	
31365289-3	2019	Here we showed that bilateral microinjection of both orexin-A and orexin-B into the globus pallidus alleviated motor deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonian mice.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	175-179	hypocretin	Mus musculus	66-74	
31365289-7	2019	Orexin-A-induced increase in firing rate of pallidal neurons in MPTP parkinsonian mice was stronger than that of normal mice.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	64-68	hypocretin	Mus musculus	0-8	
30524223-8	2018	Orexin-A improved MPTP-induced impairments in both motor activity and spatial memory.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	18-22	hypocretin	Mus musculus	0-8	
30524223-13	2018	The present study demonstrated that orexin-A exerted neuroprotective effects on MPTP parkinsonian mice, which may imply orexin-A as a potential therapeutic target for PD.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	80-84	hypocretin	Mus musculus	36-44	
30524223-13	2018	The present study demonstrated that orexin-A exerted neuroprotective effects on MPTP parkinsonian mice, which may imply orexin-A as a potential therapeutic target for PD.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	80-84	hypocretin	Mus musculus	120-128	
34666119-0	2021	Orexin-B exerts excitatory effects on nigral dopaminergic neurons and alleviates motor disorders in MPTP parkinsonian mice.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	100-104	hypocretin	Mus musculus	0-8	
34666119-2	2021	The present study showed that orexin-B exerted marked excitatory effects via orexin-2 receptor on the nigral dopaminergic neurons in MPTP parkinsonian mice, while blocking orexin-2 receptor decreased the firing rate of dopaminergic neurons significantly.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	133-137	hypocretin	Mus musculus	30-38	
34666119-3	2021	Furthermore, intracerebroventricular application of orexin-B relieved the degeneration of dopaminergic neurons, increased the general spontaneous activity and alleviated motor coordination in MPTP parkinsonian mice.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	192-196	hypocretin	Mus musculus	52-60