PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17028263-5 2007 Inhibition of epidermal growth factor receptor (EGFR) and Src activities by the inhibitors PD-153035 and PP2, respectively, abolished the activation of Stat3 by DEP, suggesting that Stat3 activation by DEP requires EGFR and Src kinase activation. 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline 91-100 signal transducer and activator of transcription 3 Homo sapiens 152-157 17028263-5 2007 Inhibition of epidermal growth factor receptor (EGFR) and Src activities by the inhibitors PD-153035 and PP2, respectively, abolished the activation of Stat3 by DEP, suggesting that Stat3 activation by DEP requires EGFR and Src kinase activation. 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline 91-100 signal transducer and activator of transcription 3 Homo sapiens 182-187 15562758-6 2004 The phosphatation of STAT3 induced by HB-EGF but not by IL-6 was blocked by PD153035. 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline 76-84 signal transducer and activator of transcription 3 Homo sapiens 21-26 15562758-7 2004 CONCLUSION: The proliferation and survival of myeloma cells may be suppressed by PD153035 due to the blockage of phosphatation of STAT3 induced by the activation of EGFR. 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline 81-89 signal transducer and activator of transcription 3 Homo sapiens 130-135