PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28835349-5 2017 The results indicated a number of chalcones were potent Nrf2 activators, including 11 (licochalcone A, 4.07-fold), 12 (licochalcone B, 5.17-fold), and 19 (echinatin, 4.09-fold). echinatin 155-164 NFE2 like bZIP transcription factor 2 Homo sapiens 56-60 34510844-0 2021 Echinatin mitigates H2O2-induced oxidative damage and apoptosis in lens epithelial cells via the Nrf2/HO-1 pathway. echinatin 0-9 NFE2 like bZIP transcription factor 2 Homo sapiens 97-101 34510844-11 2021 Inhibition of Nrf2 by ML385 aggravated H2O2-induced oxidative damage and apoptosis in HLECs, and the protective effects of Ech on H2O2-induced oxidative damage and apoptosis could be restored by ML385. echinatin 123-126 NFE2 like bZIP transcription factor 2 Homo sapiens 14-18 34510844-12 2021 CONCLUSIONS: Echinatin mitigates H2O2-induced oxidative damage and apoptosis in HLECs via the Nrf2/HO-1 pathway, suggesting that Ech may be a potential drug for the treatment of cataracts. echinatin 13-22 NFE2 like bZIP transcription factor 2 Homo sapiens 94-98