PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2448651-2	1987	Most structural alterations in the amino acid side chain eliminated activity as a substrate for this enzyme, whereas modifications of any of several positions in the pteridine ring were tolerated with retention of FPGS substrate activity.	Pteridines	166-175	folylpolyglutamate synthase	Homo sapiens	214-218	
3756000-11	1986	Pteroic acid activates FPGS by lowering the Km value of the pteridine substrate.	Pteridines	60-69	folylpolyglutamate synthase	Homo sapiens	23-27