PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21541760-6 2011 Furthermore, the idebenone effect on 4-AP-evoked Ca(2+) influx and glutamate release was completely abolished by the protein kinase A (PKA) inhibitors, H89 and KT5720. idebenone 17-26 protein kinase cAMP-activated catalytic subunit alpha Rattus norvegicus 117-133 21541760-0 2011 Idebenone inhibition of glutamate release from rat cerebral cortex nerve endings by suppression of voltage-dependent calcium influx and protein kinase A. idebenone 0-9 protein kinase cAMP-activated catalytic subunit alpha Rattus norvegicus 136-152 21541760-6 2011 Furthermore, the idebenone effect on 4-AP-evoked Ca(2+) influx and glutamate release was completely abolished by the protein kinase A (PKA) inhibitors, H89 and KT5720. idebenone 17-26 protein kinase cAMP-activated catalytic subunit alpha Rattus norvegicus 135-138 21541760-7 2011 On the basis of these results, it was concluded that idebenone inhibits glutamate release from rat cortical synaptosomes and this effect is linked to a decrease in [Ca(2+)](C) contributed by Ca(2+) entry through presynaptic voltage-dependent Ca(2+) channels and to the suppression of PKA signaling cascade. idebenone 53-62 protein kinase cAMP-activated catalytic subunit alpha Rattus norvegicus 284-287