PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7926866-3 1994 We report here that repeated oral administration of the stimulators for the NGF synthesis, idebenone and propentofylline, produced a significant recovery of the reduced NGF content in the frontal and parietal cortices of aged rats. idebenone 91-100 nerve growth factor Rattus norvegicus 76-79 7562397-7 1995 We demonstrate here that the oral administration of propentofylline, idebenone and trimethylquinone derivative, potent in vitro NGF synthesis stimulators, induced the increase in NGF protein and mRNA, and in choline acetyltransferase activity, in basal forebrain-lesioned and aged rats, but not in intact young rats. idebenone 69-78 nerve growth factor Rattus norvegicus 128-131 7562397-7 1995 We demonstrate here that the oral administration of propentofylline, idebenone and trimethylquinone derivative, potent in vitro NGF synthesis stimulators, induced the increase in NGF protein and mRNA, and in choline acetyltransferase activity, in basal forebrain-lesioned and aged rats, but not in intact young rats. idebenone 69-78 nerve growth factor Rattus norvegicus 179-182 8058112-0 1994 Oral administration of idebenone induces nerve growth factor in the brain and improves learning and memory in basal forebrain-lesioned rats. idebenone 23-32 nerve growth factor Rattus norvegicus 41-60 8058112-5 1994 We demonstrate here that the oral administration of idebenone, a potent in vitro nerve growth factors synthesis stimulator, induced an increase in nerve growth factor protein and mRNA, and in choline acetyltransferase activity, in basal forebrain lesioned rats, but not in intact rats. idebenone 52-61 nerve growth factor Rattus norvegicus 81-100 8058112-7 1994 These results suggest that idebenone stimulated nerve growth factor synthesis in vivo and ameliorates the behavioral deficits which were accompanied with the recovery of the reduced choline acetyltransferase activity in the basal forebrain-lesioned rats. idebenone 27-36 nerve growth factor Rattus norvegicus 48-67 11040339-0 2000 CV-2619 protects cultured astrocytes against reperfusion injury via nerve growth factor production. idebenone 0-7 nerve growth factor Rattus norvegicus 68-87 11040339-6 2000 The effect of CV-2619 on H(2)O(2) exposure-induced cytotoxicity was blocked by cycloheximide and anti-NGF antibody. idebenone 14-21 nerve growth factor Rattus norvegicus 102-105 11040339-8 2000 These findings suggest that the effect of CV-2619 is mediated at least partly by NGF production in astrocytes and that ERK and phosphatidylinositol-3 kinases play a role in the downstream mechanism. idebenone 42-49 nerve growth factor Rattus norvegicus 81-84 7926866-3 1994 We report here that repeated oral administration of the stimulators for the NGF synthesis, idebenone and propentofylline, produced a significant recovery of the reduced NGF content in the frontal and parietal cortices of aged rats. idebenone 91-100 nerve growth factor Rattus norvegicus 169-172