PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25421718-6 2015 These results suggest that the combination of insulin and idebenone could decrease the BBB permeability in diabetic rats by upregulating the expression of occludin, claudin-5, and ZO-1 and that the ROS/AGE/RAGE/NF-kappaB signal pathway might be involved in the process. idebenone 58-67 claudin 5 Rattus norvegicus 165-174