PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3720849-7 1986 In models for postsynaptic DA receptor stimulation (induction of stereotypy in rats, reversal of reserpine-induced immobility of mice) N-0500 was found to be as effective as RU-29717 in inducing stereotyped behaviors in rats, but was much less effective than RU-29717 in restoring the mobility of reserpinized mice, suggesting a selectivity for D-2 DA receptors by N-0500 in contrast to the mixed D-1/D-2 receptor activity of RU-29717. naxagolide 135-141 dopamine receptor D2 Mus musculus 401-413 3720849-10 1986 On the basis of its very potent in vivo central D-2 dopamine receptor activities and its in vitro selectivity, N-0500, being the most potent compound within the series, is a much more specifically acting drug than many of the dopaminergic ergolines and might therefore be a good candidate for the treatment of Parkinson"s disease. naxagolide 111-117 dopamine receptor D2 Mus musculus 48-69