PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2449686-3	1987	NREBP and alpha-FP manifested a very close hormonal specificity of affinity differing from SEBP specificity: both proteins bound intensively estrone and estradiol, to a lesser degree, estriol, and did not bind androgens and hexestrol.	Estrone	141-148	alpha-fetoprotein	Rattus norvegicus	10-18	
60142-3	1976	Rat alpha-foetoprotein (AFP) was shown to inhibit the formation of water soluble metabolities of oestrone and oestradiol by incubation with microsomes from rat liver in the presence of NADPH.	Estrone	97-105	alpha-fetoprotein	Rattus norvegicus	4-22	
60142-3	1976	Rat alpha-foetoprotein (AFP) was shown to inhibit the formation of water soluble metabolities of oestrone and oestradiol by incubation with microsomes from rat liver in the presence of NADPH.	Estrone	97-105	alpha-fetoprotein	Rattus norvegicus	24-27	
1716990-2	1991	They had differential inhibitory effects (NDGA greater than equol greater than enterolactone greater than enterodiol) on the binding of estrone and estradiol to rat AFP and the binding of unsaturated fatty acid to both rat and human AFP.	Estrone	136-143	alpha-fetoprotein	Rattus norvegicus	165-168	
1716990-4	1991	The apparent dissociation constants (Kd) for phytoestrogens binding to AFP were: Kd NDGA = 5 +/- 1.2.10(-7) M, Kd equol = 6.7 +/- 0.8.10(-6) M, Kd enterolactone = 1.7 +/- 0.4.10(-5) M and Kd enterodiol = 2.2 +/- 0.6.10(-5) M. The Kd for estrone binding to rat AFP was increased by increasing concentrations of equol, but the number of esterone binding sites remained unchanged.	Estrone	237-244	alpha-fetoprotein	Rattus norvegicus	71-74	
2421727-1	1986	Incubation of rat alpha-fetoprotein (AFP) with mM concentrations of N-ethylmaleimide (MalNEt) at 22 degrees, pH7.8 for several hours yields a form of AFP with an equilibrium dissociation constant of 0.1 nM for estrone.	Estrone	210-217	alpha-fetoprotein	Rattus norvegicus	18-35	
2421727-1	1986	Incubation of rat alpha-fetoprotein (AFP) with mM concentrations of N-ethylmaleimide (MalNEt) at 22 degrees, pH7.8 for several hours yields a form of AFP with an equilibrium dissociation constant of 0.1 nM for estrone.	Estrone	210-217	alpha-fetoprotein	Rattus norvegicus	37-40	
2421727-1	1986	Incubation of rat alpha-fetoprotein (AFP) with mM concentrations of N-ethylmaleimide (MalNEt) at 22 degrees, pH7.8 for several hours yields a form of AFP with an equilibrium dissociation constant of 0.1 nM for estrone.	Estrone	210-217	alpha-fetoprotein	Rattus norvegicus	150-153	
2578598-0	1985	Alpha-fetoprotein favours accumulation of estrone but not arachidonic acid into the fetal and new-born rat brain.	Estrone	42-49	alpha-fetoprotein	Rattus norvegicus	0-17