PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22848414-5 2012 Through chromatin immunoprecipitation and luciferase reporter assays we corroborated these findings both in vivo and in vitro, showing that Ikaros deleted isoforms lacked the ability to directly regulate a large group of the genes in the signature, such as IGLL1, BLK, EBF1, MSH2, BUB3, ETV6, YES1, CDKN1A (p21), CDKN2C (p18) and MCL1. ikaros 140-146 BLK proto-oncogene, Src family tyrosine kinase Homo sapiens 264-267