PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34664067-8	2021	UHPLC-fourier-transform mass spectrometry detection results revealed that five alkaloids showed obvious AChE inhibitory activities including coptisin, epiberberine, jatrorrhizine, berberine and palmatine.	palmatine	194-203	acetylcholinesterase (Cartwright blood group)	Homo sapiens	104-108	
24793543-0	2014	Synergistic inhibition on acetylcholinesterase by the combination of berberine and palmatine originally isolated from Chinese medicinal herbs.	palmatine	83-92	acetylcholinesterase (Cartwright blood group)	Homo sapiens	26-46	
24793543-5	2014	Our results showed that the combination of berberine and palmatine inhibited acetylcholinesterase in a mixed competitive pattern.	palmatine	57-66	acetylcholinesterase (Cartwright blood group)	Homo sapiens	77-97	
24164032-7	2013	Seven isoquinoline alkaloids, namely jatrorrhizine, epiberberine, columbamine, coptisine, corysamine, palmatine and berberine were identified to be active as the inhibitors of ACHE.	palmatine	102-111	acetylcholinesterase (Cartwright blood group)	Homo sapiens	176-180	
34664067-9	2021	The relative AChE inhibitory activities of jatrorrhizine, berberine and palmatine in the Coptidis Rhizoma sample were equal to that of 257.0, 2355 and 283.9 mug/mL of galanthamine, respectively.	palmatine	72-81	acetylcholinesterase (Cartwright blood group)	Homo sapiens	13-17	
34033838-4	2021	In order to gain insights into how these alkaloids could inhibit AChE, berberine, palmatine, and cyclanoline were selected to investigate in terms of binding orientation and their key interactions with AChE using molecular docking and molecular dynamics simulations and quantum chemical calculations.	palmatine	82-91	acetylcholinesterase (Cartwright blood group)	Homo sapiens	202-206