PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31285280-6 2019 These data reveal a previously unrecognized lysosomal P2RX4- and ADCY1-dependent signaling cascade as a pathway essential for CAD-induced lysosome-dependent cell death and encourage further investigations to find the most potent combinations of CADs and cAMP-inducing drugs for cancer therapy. CyADIC regimen 245-249 adenylate cyclase 1 Homo sapiens 65-70