PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33535454-5 2021 Conversely, the aforementioned tetrahydrofurofuranoid lignans competitively inhibited UGT1A3-catalyzed chenodeoxycholic acid 24-acyl-glucuronidation with 39.8, 24.3, 15.1, 37.6, and 66.8 muM, respectively in pooled human liver microsomes. tetrahydrofurofuranoid 31-53 UDP glucuronosyltransferase family 1 member A3 Homo sapiens 86-92 33535454-6 2021 These in vitro results suggest the necessity of evaluating whether the five tetrahydrofurofuranoid lignans can cause drug-drug interactions with UGT1A1 and UGT1A3 substrates in vivo. tetrahydrofurofuranoid 76-98 UDP glucuronosyltransferase family 1 member A3 Homo sapiens 156-162