PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25968479-5 2015 Leptin deficient mice depicted permanently increased water diffusion parameters under all feeding conditions as compared to wild type controls, without important changes upon fasting or recovery. Water 53-58 leptin Mus musculus 0-6 17463181-4 2007 Therefore, we sought to determine whether leptin would alter the expression of genes involved in water and ion transport across the gallbladder epithelium. Water 97-102 leptin Mus musculus 42-48 17463181-7 2007 Leptin repletion upregulated the expression of aquaporin 1 water channel by 1.3-fold and downregulated aquaporin 4 by 2.3-fold. Water 59-64 leptin Mus musculus 0-6 17463181-12 2007 Thus leptin, an adipocyte-derived cytokine involved with satiety and energy balance, influences gallbladder bile volume, sodium, and pH as well as multiple inflammatory cytokine genes and genes related to water, sodium, chloride, and bicarbonate transport. Water 205-210 leptin Mus musculus 5-11 29958959-8 2018 RESULTS: The LEP showed an interesting water-holding capacity and effective foaming and emulsifying properties. Water 39-44 leptin Mus musculus 13-16 23462572-3 2013 After the injection of a high replacement dose (0.04 mg/kg) and two pharmacologic doses (4 and 8 mg/kg) of leptin, brain water contents increased significantly compared with that of control mice (P<0.05), which was confirmed when comparing the results with leptin-deficient ob/ob and wild-type (WT) mice (78.8%+-0.6% versus 79.7%+-0.6%, P<0.05). Water 121-126 leptin Mus musculus 107-113 23438451-3 2013 Here we demonstrate that in obesity, early steatohepatitic lesions induced by the water disinfection byproduct bromodichloromethane are mediated by increased oxidative stress and leptin which act in synchrony to potentiate disease progression. Water 82-87 leptin Mus musculus 179-185