PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28076507-7 2016 RESULTS:: Clinical scores, TNF-alpha, IL-1beta, liver/kidney proof levels, and lung injury were significantly reduced in coconut water+NaCl 3%+simvastatin group treated rats, comparing with the other resuscitation treatments. Water 129-134 interleukin 1 beta Rattus norvegicus 38-46 34483144-7 2021 The anti-inflammatory effect of betaine was confirmed by the downregulation of pro-inflammation-related molecules, including vascular cell adhesion molecule 1 and interleukin-1beta in the retinas of rats with EAU. Water 209-212 interleukin 1 beta Rattus norvegicus 163-180 31281400-19 2019 The protective effect of special electromagnetic field treated water and far infrared rays on endotoxin-induced acute respiratory distress syndrome may result from their role in reducing the levels of IL-1beta and IL-6 in serum and the expression level of p65 protein in lung tissue, in addition to reliving inflammatory response, lung coefficient, and lungs edema. Water 63-68 interleukin 1 beta Rattus norvegicus 201-209 28298306-7 2017 Finally, stable overexpression of miR-372 inhibitor in hNSC rescued the IL-1beta-induced impairment as shown by significant improvements in tissue water content, myeloperoxidase activity, and behavioral assessments in SCI rats. Water 147-152 interleukin 1 beta Rattus norvegicus 72-80 27466288-0 2016 Repeated Water Avoidance Stress Alters Mucosal Mast Cell Counts, Interleukin-1beta Levels with Sex Differences in the Distal Colon of Wistar Rats. Water 9-14 interleukin 1 beta Rattus norvegicus 65-82 26989349-0 2016 Interleukin-1beta-induced reduction of tissue water diffusion in the juvenile rat brain on ADC MRI is not associated with (31)P MRS-detectable energy failure. Water 46-51 interleukin 1 beta Rattus norvegicus 0-17 27222637-0 2016 Erratum to: Interleukin-1beta-induced reduction of tissue water diffusion in the juvenile rat brain on ADC MRI is not associated with (31)P MRS-detectable energy failure. Water 58-63 interleukin 1 beta Rattus norvegicus 12-29 26989349-1 2016 BACKGROUND: It has long been known that an intrastriatal microinjection of the archetypal pro-inflammatory cytokine, interleukin-1beta (IL-1beta), in juvenile rats induces a chronic reduction in the apparent diffusion coefficient (ADC) of tissue water on magnetic resonance imaging (MRI). Water 246-251 interleukin 1 beta Rattus norvegicus 117-134 26989349-1 2016 BACKGROUND: It has long been known that an intrastriatal microinjection of the archetypal pro-inflammatory cytokine, interleukin-1beta (IL-1beta), in juvenile rats induces a chronic reduction in the apparent diffusion coefficient (ADC) of tissue water on magnetic resonance imaging (MRI). Water 246-251 interleukin 1 beta Rattus norvegicus 136-144 19217659-3 2009 Third ventricle injections of IL-1beta significantly inhibited the increase in water intake observed in those situations. Water 79-84 interleukin 1 beta Rattus norvegicus 30-38 23984371-8 2013 Water immersion restraint increased gastric mucosal ulcer and hemorrhage, tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, and IL-6 levels but failed to affect mucosal lipid peroxidation and mucus secretion compared with non-WIR. Water 0-5 interleukin 1 beta Rattus norvegicus 109-131 22321167-4 2012 Inversely, the more severe elevations of hepatic water-soluble parts of TC and TG were found in the HFD+CS group, as the elevations of low-density lipoprotein cholesterol, very low-density lipoprotein cholesterol in liver and serum, tumor necrosis factor-alpha, interleukin-1beta and malondialdehyde in liver. Water 49-54 interleukin 1 beta Rattus norvegicus 262-279 22215116-2 2012 Intrastriatal microinjection of IL-1beta induces a chronic reduction in the apparent diffusion coefficient (ADC) of tissue water, which may be indicative of metabolic failure as established by in vivo models of acute cerebral ischaemia. Water 123-128 interleukin 1 beta Rattus norvegicus 32-40 19217659-7 2009 Furthermore, the inhibitory effects of IL-1beta on water intake cannot be attributed to sickness-like effects induced by these compounds, since an aversion test excluded this possibility. Water 51-56 interleukin 1 beta Rattus norvegicus 39-47 17583206-5 2007 RESULT: Two kinds of water abstract induced significantly renal injury in rats, IL-1beta, IL-6 levels in renal homogenate were significantly increased compared with controls, histological section showed inflammatory cell infiltration play important role in renal tubulointerstitium damage. Water 21-26 interleukin 1 beta Rattus norvegicus 80-88 12231480-7 2002 IL-1beta reduced the net absorption of water and chloride. Water 39-44 interleukin 1 beta Rattus norvegicus 0-8 16375968-0 2006 Inhibition of water intake by the central administration of IL-1beta in rats: role of the central opioid system. Water 14-19 interleukin 1 beta Rattus norvegicus 60-68 16375968-1 2006 In the present study we investigated, the effect of third ventricle injections of IL-1beta on water intake, in rats, induced by three different physiological stimuli: dehydration induced by water deprivation, hypernatremia associated with hyperosmolarity induced by intragastric salt load, and hypovolemia produced by subcutaneous polytethyleneglycol administration. Water 94-99 interleukin 1 beta Rattus norvegicus 82-90 16554088-0 2006 Role of the central opioid system in the inhibition of water and salt intake induced by central administration of IL-1beta in rats. Water 55-60 interleukin 1 beta Rattus norvegicus 114-122 16554088-1 2006 In the present study we investigated, the effect of third ventricle injections of IL-1beta on water and salt intake in fluid-deprived and sodium-depleted rats. Water 94-99 interleukin 1 beta Rattus norvegicus 82-90 16554088-2 2006 Central administration of IL-1beta significantly reduced water and salt intake in fluid-deprived animals and decreased salt intake in sodium-depleted rats. Water 57-62 interleukin 1 beta Rattus norvegicus 26-34 16554088-5 2006 The present results suggest that the activation of the central interleukinergic component by IL-1beta impairs the increase in water and salt intake induced by water deprivation and the enhancement in sodium appetite that follows sodium depletion. Water 126-131 interleukin 1 beta Rattus norvegicus 93-101 15683432-9 2005 The gastric content of MPO, TNF-alpha and IL-1beta were all increased after water-immersion stress and reduced to near normal levels by ATL-146e. Water 76-81 interleukin 1 beta Rattus norvegicus 42-50 16375968-2 2006 Central administration of IL-1beta at the doses of 4 and 8 ng reduced water intake in all three conditions studied. Water 70-75 interleukin 1 beta Rattus norvegicus 26-34 11050138-3 2000 Four hours after injection of IL-1beta (1 ng in 1 microliter), cerebral blood volume was significantly increased, the blood-brain barrier (BBB) became permeable to intravenously administered contrast agent between 4.5 and 5 hr, and the apparent diffusion coefficient (ADC) of brain water fell by 6 hr (5.42 +/- 0. Water 282-287 interleukin 1 beta Rattus norvegicus 30-38 11050138-9 2000 The presence of neutrophils within the brain parenchyma significantly contributed to the IL-1beta-induced changes in cerebral blood volume and the ADC of brain water. Water 160-165 interleukin 1 beta Rattus norvegicus 89-97 8653552-2 1995 IL-1 beta decreased food and water intake and elevated body temperature. Water 29-34 interleukin 1 beta Rattus norvegicus 0-9 9916024-10 1999 Furthermore, treatment with a water-permeable form of cholesterol that bypasses the requirement for StAR partially restored hCG-stimulated testosterone secretion from testes isolated from rats treated icv with IL-1beta. Water 30-35 interleukin 1 beta Rattus norvegicus 210-218 8971291-12 1996 Water immersion stress increased gastric mucosal IL-1 beta and IL-2 contents 6 h after stress treatment, and these increases were prevented by FK506. Water 0-5 interleukin 1 beta Rattus norvegicus 49-58 8594930-2 1995 Intraperitoneal injection of 0.12 nmol/rat IL-1 beta decreased food and water intake and elevated body temperature. Water 72-77 interleukin 1 beta Rattus norvegicus 43-52 7716222-2 1995 Intraperitoneal (ip) injection of IL-1 beta suppressed food and water intake and elevated rectal temperature. Water 64-69 interleukin 1 beta Rattus norvegicus 34-43 7615197-2 1995 The aim of this study was to investigate the mechanism of action of IL-1 beta on colonic net water flux and the role of tachykinins and nitric oxide. Water 93-98 interleukin 1 beta Rattus norvegicus 68-77 8685078-2 1995 CLS.H2O given by the oral route (300 mg kg(-1)) significantly reduced neutrophil infiltration into the airway lumen induced by intratracheal injection of IL-1 beta in rats. Water 4-7 interleukin 1 beta Rattus norvegicus 154-163 7709417-8 1995 In contrast, administration of anti-IL-1 beta and ZnPP into the left cerebral ventricle attenuated the postischemic increase of brain water content and decreased the size of brain infarction (83.5 +/- 2.0% and 79.9 +/- 2.0% in the dorsal and ventral parts of the caudate putamen, respectively, in rats treated with 10 micrograms anti-IL-1 beta; P < .01). Water 134-139 interleukin 1 beta Rattus norvegicus 36-45 7709417-10 1995 CONCLUSIONS: Application of rhIL-1 beta augmented the increase of brain water content, and application of anti-IL-1 beta depressed the increase of water content. Water 72-77 interleukin 1 beta Rattus norvegicus 30-39 7716222-3 1995 The suppressive effect of IL-1 beta on water intake was converted to an increase when 4.0 mM Rg1 was continuously infused into the third cerebroventricle (ICV) at a rate of 0.966 microliters/h. Water 39-44 interleukin 1 beta Rattus norvegicus 26-35 7716222-6 1995 These results suggest that sustained ICV infusion of Rg1 may modulate the effects of IL-1 beta on ingestive behaviors, i.e., increase in water intake and sustained decrease in food intake, resulting in a lowering of body temperature. Water 137-142 interleukin 1 beta Rattus norvegicus 85-94 7824567-0 1994 Reduction in food and water intake induced by microinjection of interleukin-1 beta in the ventromedial hypothalamus of the rat. Water 22-27 interleukin 1 beta Rattus norvegicus 64-82 7824567-4 1994 IL-1 beta (5 ng) diminished food and water consumption by 45 and 30%, respectively, and decreased body weight for at least 24 h postinjection in rats fed ad lib. Water 37-42 interleukin 1 beta Rattus norvegicus 0-9 8194694-1 1994 BACKGROUND/AIMS: Interleukin 1 beta (IL-1 beta) is known to regulate intestinal ion and water transport in vitro through prostaglandin release. Water 88-93 interleukin 1 beta Rattus norvegicus 17-35 8194694-1 1994 BACKGROUND/AIMS: Interleukin 1 beta (IL-1 beta) is known to regulate intestinal ion and water transport in vitro through prostaglandin release. Water 88-93 interleukin 1 beta Rattus norvegicus 37-46 8194694-2 1994 This study investigated the effect of IL-1 beta on colonic net water flux in vivo to determine its nature (nerve mediation versus action on the epithelium), the mediators involved, and its relationship with mast cell degranulation. Water 63-68 interleukin 1 beta Rattus norvegicus 38-47 1386466-0 1992 Intracerebroventricular administration of a specific IL-1 receptor antagonist blocks food and water intake suppression induced by interleukin-1 beta. Water 94-99 interleukin 1 beta Rattus norvegicus 130-148 1641429-1 1992 Decrease in water intake after intraperitoneal injection of interleukin-1 beta (IL-1 beta) was studied in the rat. Water 12-17 interleukin 1 beta Rattus norvegicus 60-78 1641429-1 1992 Decrease in water intake after intraperitoneal injection of interleukin-1 beta (IL-1 beta) was studied in the rat. Water 12-17 interleukin 1 beta Rattus norvegicus 80-89 1641429-3 1992 Interleukin-1 beta also decreased spontaneous intake of water but not that of 1.8% saline. Water 56-61 interleukin 1 beta Rattus norvegicus 0-18 1641429-4 1992 The results suggest that the decrease in water intake by IL-1 beta is caused, at least in part, by suppression of osmotic thirst but not by general suppression of behavior. Water 41-46 interleukin 1 beta Rattus norvegicus 57-66 1641429-6 1992 Pretreatment with indomethacin blocked the decrease in water intake by IL-1 beta, suggesting the involvement of production of prostaglandins. Water 55-60 interleukin 1 beta Rattus norvegicus 71-80 2046458-2 1991 The intracerebroventricular (icv) administration of IL-1 beta significantly inhibited the occurrence of water-immersion restraint stress-induced gastric erosion at doses of 200 ng, 500 ng and 1 microgram, whereas the intravenous (iv) administration of IL-1 beta altered the occurrence of gastric erosion only at a dose of 1 microgram. Water 104-109 interleukin 1 beta Rattus norvegicus 52-61