PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19931295-7 2010 Aryl hydrocarbon receptor (AhR) and B[alpha]P-related H(2)O(2) formation were involved in the reduced expression of HMG-CoA reductase and in the remodeling of membrane microdomains. Water 54-59 3-hydroxy-3-methylglutaryl-CoA reductase Rattus norvegicus 116-133 4052444-1 1985 A water-soluble derivative of cholesterol, methoxypolyoxyethylated (MPOE) cholesterol, has been synthesized and used to study the regulation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the key regulatory enzyme in cholesterol biosynthesis. Water 2-7 3-hydroxy-3-methylglutaryl-CoA reductase Rattus norvegicus 144-201