PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17869387-5 2008 Co-crystal structures of inhibitors bound to Wee1 show that the pyrrolo[3,4-c]carbazole scaffold binds in the ATP-binding site, with N-6 substituents involved in H-bonding to conserved water molecules. Water 185-190 WEE1 G2 checkpoint kinase Homo sapiens 45-49