PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26253170-0	2015	A New Fungal Diterpene Induces VDAC1-dependent Apoptosis in Bax/Bak-deficient Cells.	bakuchiol	64-67	BCL2-associated X protein	Mus musculus	60-63	
18678651-8	2008	siRNA-treated BAK(-/-) BAX(-/-) double-knockout mouse embryonic fibroblasts failed to activate capase-3 or increase TUNEL staining but instead exhibited autophagy, as demonstrated by proteolytic processing of microtubule-associated protein 1 light chain 3 (LC3) and translocation of transfected green fluorescent protein-LC3 from the nucleus to punctate cytoplasmic structures.	bakuchiol	14-17	BCL2-associated X protein	Mus musculus	23-26	
21911424-10	2011	In vivo, mice with a Bak(-/-) Bax(-/-) hematopoietic system were protected against thrombocytopenia induced by the chemotherapeutic agent carboplatin.	bakuchiol	21-24	BCL2-associated X protein	Mus musculus	30-33	
26760337-3	2010	Antiapoptotic members of the Bcl-2 family (B cell CLL/lymphoma 2), that belong to the intrinsic route of the activation of caspases, such as Bcl-xL (extra-large B-cell lymphoma) and Bcl-w (Bcl-2-like 2), act predominantly to prevent that pro-apoptotic members, such as Bax (Bcl-2-associated X protein) and Bak (Bcl-2 relative bak) lead to cell death.	bakuchiol	326-329	BCL2-associated X protein	Mus musculus	269-272	
26760337-3	2010	Antiapoptotic members of the Bcl-2 family (B cell CLL/lymphoma 2), that belong to the intrinsic route of the activation of caspases, such as Bcl-xL (extra-large B-cell lymphoma) and Bcl-w (Bcl-2-like 2), act predominantly to prevent that pro-apoptotic members, such as Bax (Bcl-2-associated X protein) and Bak (Bcl-2 relative bak) lead to cell death.	bakuchiol	326-329	BCL2-associated X protein	Mus musculus	274-309	
23846222-7	2013	Ssd also proved to be a potent cytotoxic agent in apoptosis-defective or apoptosis-resistant mouse embryonic fibroblast cells, which either lack caspases 3, 7 or 8 or had the Bax-Bak double knockout.	bakuchiol	179-182	BCL2-associated X protein	Mus musculus	175-178	
15272317-1	2004	Photoreceptors of bax(-/-)bak(-/-) but neither bax(-/-) mice nor bak(-/-) mice are protected from developmental apoptosis, suggesting that bax(-/-)bak(-/-) photoreceptors may also be protected from pathologic apoptosis.	bakuchiol	26-29	BCL2-associated X protein	Mus musculus	18-21	
18670882-5	2008	Here we report that m38.5 protein encoded by murine cytomegalovirus, which is unrelated to vMIA in its amino acid sequence, delays death receptor ligation-induced cell death, and that m38.5 associates with Bax, recruits it to mitochondria, and blocks Bax-mediated but not Bak-mediated mitochondrial outer membrane permeabilization.	bakuchiol	272-275	BCL2-associated X protein	Mus musculus	206-209	
18272391-0	2008	Bax deficiency promotes an up-regulation of Bim(EL) and Bak during striatal and cortical postnatal development, and after excitotoxic injury.	bakuchiol	56-59	BCL2-associated X protein	Mus musculus	0-3	
18272391-2	2008	Compared with wild-type animals, Bax knockout mice showed region- and time-dependent increases in pro-apoptotic proteins Bak and Bim(EL).	bakuchiol	121-124	BCL2-associated X protein	Mus musculus	33-36	
18191336-5	2008	RESULTS: Radiation exposure of Bax- and Bak-deficient mice, both expressing a wild-type acid sphingomyelinase (ASMase) phenotype, indicated that Bax and Bak are both mandatory, though mutually independent, for the intestinal endothelial apoptotic response.	bakuchiol	40-43	BCL2-associated X protein	Mus musculus	145-148	
17230516-8	2007	More importantly, vaccination with E7-presenting DCs transfected with BAK/BAX siRNA generated a strong therapeutic effect against an E7-expressing tumor in vaccinated mice, compared with DCs transfected with control siRNA.	bakuchiol	70-73	BCL2-associated X protein	Mus musculus	74-77	
16275996-7	2005	On the other hand, SV40 immortalized mouse embryonic fibroblasts derived from Bax-Bak double knockout mice were significantly more resistant to guggulsterone-induced cell killing compared with wild-type cells.	bakuchiol	82-85	BCL2-associated X protein	Mus musculus	78-81	
12244308-3	2002	We found that the development and selection of Bak(-/-)Bax(-/-) thymocytes was disrupted, with altered representation of thymic subsets and resistance to both death-by-neglect and antigen receptor-induced apoptosis.	bakuchiol	47-50	BCL2-associated X protein	Mus musculus	55-58	
12813466-8	2003	The data reported herein indicate that LMP does not suffice to trigger caspase activation and that Bax/Bak-dependent MMP is a critical step of LMP-induced cell death.	bakuchiol	103-106	BCL2-associated X protein	Mus musculus	99-102	
12244308-4	2002	Elimination of Bak(-/-)Bax(-/-) T cells that responded to endogenous superantigen was also reduced.	bakuchiol	15-18	BCL2-associated X protein	Mus musculus	23-26