PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17996726-4 2008 Mevastatin treatment transcriptionally and translationally up-regulated RhoA expression in the cells by negative feedback mechanism. mevastatin 0-10 ras homolog family member A Homo sapiens 72-76 17996726-5 2008 While TSA enhanced mevastatin-induced RhoA up-regulation, more importantly, it also accelerated mevastatin-mediated depletion of membrane-bound (geranylgeranylated) RhoA. mevastatin 19-29 ras homolog family member A Homo sapiens 38-42 17996726-5 2008 While TSA enhanced mevastatin-induced RhoA up-regulation, more importantly, it also accelerated mevastatin-mediated depletion of membrane-bound (geranylgeranylated) RhoA. mevastatin 96-106 ras homolog family member A Homo sapiens 165-169 19888963-6 2009 KEY RESULTS: Mevastatin reduced the synthesis of cholesterol, geranylgeranyl pyrophosphate and ubiquinone, mitochondrial electron transport, activity of RhoA and Rac, and cell proliferation, accompanied by increased cell death. mevastatin 13-23 ras homolog family member A Homo sapiens 153-157 16405649-9 2006 As expected, the inhibitory effect of mevastatin was associated with altered subcellular localization of the Rho GTPases, RhoA and cdc42, indicating decreased prenylation of these molecules. mevastatin 38-48 ras homolog family member A Homo sapiens 122-126