PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26359950-0	2015	Mevastatin ameliorates sphingosine 1-phosphate-induced COX-2/PGE2-dependent cell migration via FoxO1 and CREB phosphorylation and translocation.	mevastatin	0-10	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	55-60	
26359950-3	2015	However, the mechanisms underlying S1P-evoked COX-2-dependent cell migration, which is modulated by mevastatin in human tracheal smooth muscle cells (HTSMCs) remain unclear.	mevastatin	100-110	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	46-51	
11591701-6	2001	Treatment of cells with 25 microm mevastatin or lovastatin resulted in the induction of COX-2 and increase in prostacyclin production.	mevastatin	34-44	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	88-93	
26359950-10	2015	Finally, we showed that pretreatment with mevastatin markedly reduced S1P-induced cell migration and COX-2/PGE2 production via a PPARgamma-dependent signalling pathway.	mevastatin	42-52	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	101-106	
26359950-11	2015	CONCLUSIONS AND IMPLICATIONS: Mevastatin attenuates the S1P-induced increased expression of COX-2 and cell migration via the regulation of FoxO1 and CREB phosphorylation and translocation by PPARgamma in HTSMCs.	mevastatin	30-40	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	92-97