PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16443326-0	2006	Inhibition of the ERK/MAP kinase pathway attenuates heme oxygenase-1 expression and heme-mediated neuronal injury.	Heme	52-56	mitogen-activated protein kinase 1	Homo sapiens	18-21	
19371583-8	2009	These results suggest that reduction in HO activity may contribute to the protective effect of MEK and ERK inhibitors against heme-mediated neuronal injury.	Heme	126-130	mitogen-activated protein kinase 1	Homo sapiens	103-106	
19133234-0	2009	Stress-induced overexpression of the heme-regulated eIF-2alpha kinase is regulated by Elk-1 activated through ERK pathway.	Heme	37-41	mitogen-activated protein kinase 1	Homo sapiens	110-113	
15265937-6	2004	Inhibition of ERK and PI3K pathways abolished heme-protective effects upon human neutrophils, suggesting the involvement of the Ras/Raf/MAPK and PI3K pathway on this effect.	Heme	46-50	mitogen-activated protein kinase 1	Homo sapiens	14-17	
15265937-7	2004	Confirming the involvement of these pathways in the modulation of the antiapoptotic effect, heme induces Akt phosphorylation and ERK-2 nuclear translocation in neutrophils.	Heme	92-96	mitogen-activated protein kinase 1	Homo sapiens	129-134