PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14742312-0	2004	Plutonium targets the p16 gene for inactivation by promoter hypermethylation in human lung adenocarcinoma.	Plutonium	0-9	cyclin dependent kinase inhibitor 2A	Homo sapiens	22-25	
14742312-7	2004	Stratification of plutonium exposure into tertiles also revealed a striking dose response for methylation of the p16 gene (P = 0.008).	Plutonium	18-27	cyclin dependent kinase inhibitor 2A	Homo sapiens	113-116	
14742312-12	2004	Here we demonstrate that exposure to plutonium may elevate the risk for adenocarcinoma through specifically targeting the p16 gene for inactivation by promoter methylation.	Plutonium	37-46	cyclin dependent kinase inhibitor 2A	Homo sapiens	122-125