PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26514304-0 2015 Chaetocin inhibits RANKL-induced osteoclast differentiation through reduction of Blimp1 in Raw264.7 cells. chaetocin 0-9 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 19-24 26514304-5 2015 In this study, we examine the effect of chaetocin on RANKL-induced osteoclast differentiation and cell growth. chaetocin 40-49 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 53-58 26514304-9 2015 KEY FINDINGS: Here we show that chaetocin dose-dependently reduced RANKL-induced osteoclast differentiation and cell growth via Blimp1 downregulation which results in the upregulation of osteoclast differentiation inhibitors and cell growth suppressors. chaetocin 32-41 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 67-72 26514304-11 2015 SIGNIFICANCE: These results suggest that chaetocin suppresses RANKL-induced osteoclastogenesis and cell growth through blimp1 downregulation, followed by induction of anti-osteoclastogenic genes and cell growth suppressors, without inhibition of Suv39h1. chaetocin 41-50 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 62-67