PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20210309-1 2010 The first total synthesis of (+)-chaetocin has been accomplished in nine steps starting from known N-Cbz-N-Me-serine using radical alpha-bromination reaction of diketopiperazine 10 and Co(I)-mediated reductive dimerization reaction of 12 as key reactions. chaetocin 29-42 mitochondrially encoded cytochrome c oxidase I Homo sapiens 185-189