PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26945041-7 2016 We found that Hsp90 protein binds PS-ASOs containing locked-nucleic-acid (LNA) or constrained-ethyl-bicyclic-nucleic-acid ((S)-cEt) modifications much more avidly than 2"-O-methoxyethyl (MOE). ps-asos 34-41 heat shock protein 90 alpha family class A member 1 Homo sapiens 14-19 26945041-10 2016 Reduction of Hsp90 protein decreased activity of PS-ASOs with 5"-LNA or 5"-cEt wings, but not with 5"-MOE wing. ps-asos 49-56 heat shock protein 90 alpha family class A member 1 Homo sapiens 13-18