PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3525194-0 1986 Cerebral renin-angiotensin mediation of isoproterenol-induced thirst in the dog. Isoproterenol 40-53 renin Canis lupus familiaris 9-14 8102503-9 1993 Subsequent infusion of isoproterenol (0.2 microgram min-1 kg-1 body wt) to stimulate beta-adrenoceptor activity increased renin release from 13 +/- 4 micrograms AI min-1 to 68 +/- 8 micrograms AI min-1 during ureteral occlusion. Isoproterenol 23-36 renin Canis lupus familiaris 122-127 3525194-1 1986 Pretreatment of dogs with s.c. isoproterenol (10 micrograms/kg) caused a significant increase in drinking when 100 ng renin substrate was administered 3 min later to the lateral cerebral ventricles or subfornical organ. Isoproterenol 31-44 renin Canis lupus familiaris 118-123 2861715-6 1985 During subsequent continuous infusion of a beta-adrenergic agonist, isoproterenol (0.2 micrograms X kg-1 X min-1), constriction of the renal artery raised renin release from 0.1 +/- 0.1 to 52 +/- 11 micrograms AI X min-1, although there was no rise in PGE2 release. Isoproterenol 68-81 renin Canis lupus familiaris 155-160 2861715-8 1985 In six other dogs, phenylephrine infused during isoproterenol infusion increased renin release equally before and after indomethacin administration. Isoproterenol 48-61 renin Canis lupus familiaris 81-86 6382924-3 1984 This condition is known to increase renin release and enhance the stimulatory effects on renin release of beta-adrenergic agonists, such as isoproterenol. Isoproterenol 140-153 renin Canis lupus familiaris 89-94 6382924-5 1984 Isoproterenol infusion during afferent arteriolar dilation increased renin release but not PGE2 release both before and after indomethacin administration. Isoproterenol 0-13 renin Canis lupus familiaris 69-74 6382924-8 1984 The effect of isoproterenol on renin release is independent of prostaglandin synthesis. Isoproterenol 14-27 renin Canis lupus familiaris 31-36 6125584-6 1982 Isoproterenol elicited a significant renin release in the presence of beta-1 adrenoceptor blockade with atenolol and in the presence of selective beta-2 adrenoceptor blockade with IPS-339. Isoproterenol 0-13 renin Canis lupus familiaris 37-42 6312554-1 1983 Isoproterenol, dopamine, glucagon and dibutyryl cyclic AMP (DB-cAMP) increase renin release at low but not at control blood pressure. Isoproterenol 0-13 renin Canis lupus familiaris 78-83 6312554-6 1983 Isoproterenol infusion at low blood pressure raised renin release from 41 +/- 11 to 76 +/- 19 micrograms/min before and 54 +/- 13 to 108 +/- 31 micrograms/min during continuous infusion of theophylline. Isoproterenol 0-13 renin Canis lupus familiaris 52-57 6312554-9 1983 Theophylline infusion may augment the effect of isoproterenol on renin release by delaying the intracellular degradation of cAMP. Isoproterenol 48-61 renin Canis lupus familiaris 65-70 7044761-8 1982 Isoproterenol significantly increased total renin secretion from the slices, but not the secretion of newly synthesized renin. Isoproterenol 0-13 renin Canis lupus familiaris 44-49 6283915-2 1982 When given to slices maintained at 37 degrees C, the beta-agonists isoproterenol (ISP) and norepinephrine stimulated renin release from the slices. Isoproterenol 67-80 renin Canis lupus familiaris 117-122 6283915-2 1982 When given to slices maintained at 37 degrees C, the beta-agonists isoproterenol (ISP) and norepinephrine stimulated renin release from the slices. Isoproterenol 82-85 renin Canis lupus familiaris 117-122 17173-0 1977 [Comparative study of effect of 4 furochromone derivatives on isoprenaline induced plasma renin activity increase in anesthetized dogs. Isoproterenol 62-74 renin Canis lupus familiaris 90-95 6278576-4 1981 A beta-adrenergic stimulator, isoproterenol, did not increase renin release significantly when administered alone into the renal artery, but doubled the effect of methoxamine infusion: at control blood pressure renin release rose from 0.5 +/- 0.3 to 71 +/- 17 microgram/min during combined infusion of isoproterenol and methoxamine. Isoproterenol 30-43 renin Canis lupus familiaris 211-216 6278576-7 1981 Isoproterenol infusion at low renal perfusion pressure doubled renin release, which was not significantly altered by additional infusion of methoxamine. Isoproterenol 0-13 renin Canis lupus familiaris 63-68 6278576-10 1981 Thereby afferent arterioles are conditioned for stimulation of renin release by isoproterenol. Isoproterenol 80-93 renin Canis lupus familiaris 63-68 744084-6 1978 These data indicate that the effects of isoproterenol on drinking, urine flow, and vasopressin secretion are mediated via the renin-angiotensin system. Isoproterenol 40-53 renin Canis lupus familiaris 126-131 6103674-0 1980 Analysis of beta-adrenoceptors mediating renin release produced by isoproterenol in conscious dogs. Isoproterenol 67-80 renin Canis lupus familiaris 41-46 6103674-1 1980 Types of beta-adrenoceptors mediating renin release induced by isoproterenol were investigated in conscious dogs. Isoproterenol 63-76 renin Canis lupus familiaris 38-43 6103674-2 1980 The nonselective beta-adrenoceptor blocking drugs propranolol, D-32, and pindolol significantly inhibited increases in heart rate and plasma renin activity and a fall of blood pressure produced by intravenous infusion of isoproterenol (10 microgram . Isoproterenol 221-234 renin Canis lupus familiaris 141-146 6103674-6 1980 The selective beta 1-adrenoceptor blocking drug atenolol, at the oral dose of 6 mg/kg, which selectively suppressed isoproterenol-induced tachycardia, significantly inhibited the renin release caused by isoproterenol. Isoproterenol 203-216 renin Canis lupus familiaris 179-184 6103674-7 1980 By contrast, the renin release induced by isoproterenol was not modified by the selective beta 2-adrenoceptor blocking drug IPS-339 at an oral dose of 3 mg/kg, which fully and selectively antagonized the fall of blood pressure in response to isoproterenol. Isoproterenol 42-55 renin Canis lupus familiaris 17-22 6103674-8 1980 There was good correlation between suppression of isoproterenol-induced renin release and that of isoproterenol-induced tachycardia after various beta-adrenoceptor blocking drugs. Isoproterenol 50-63 renin Canis lupus familiaris 72-77 7008886-4 1980 The effect of prazosin on the renin release elicited by the beta-adrenoceptor agonist isoprenaline and by prostaglandin I2 was also evaluated. Isoproterenol 86-98 renin Canis lupus familiaris 30-35 396760-0 1979 Species differences in the effect of isoproterenol and pindolol on renin release in vitro. Isoproterenol 37-50 renin Canis lupus familiaris 67-72 396760-3 1979 Isoproterenol in a concentration of 3 X 10(-8) M brought about a significant increase in the renin content of the incubation media as well as the tissue slices obtained from canine kidney, however, there was no change in these parameters under similar conditions if rat kidneys were incubated. Isoproterenol 0-13 renin Canis lupus familiaris 93-98 20199-2 1977 Intravenous injection of isoproterenol increases plasma renin activity (PRA) in anesthetized dogs. Isoproterenol 25-38 renin Canis lupus familiaris 56-61 163152-5 1975 The finding that, in the lithium-treated dogs, isoproternol increased plasma renin activity but not cyclic AMP generation in the kidney suggests that the increase in plasma renin activity observed after an injection of isoproterenol is probably not mediated through the beta-adrenergic stimulus-dependent cyclic AMP system in the kidney. Isoproterenol 219-232 renin Canis lupus familiaris 173-178 1259022-1 1976 Infusion of isoproterenol intravenously in normal dogs at rates of 0.10 or 0.018 mug/min per kg body wt increased renin secretion; at the lower infusion rate arterial pressure (AP) and renal blood flow (RBF) were unchanged. Isoproterenol 12-25 renin Canis lupus familiaris 114-119 1259022-2 1976 Isoproterenol was also infused into the renal artery in normal dogs at 0.10 mug/min per kg; renin secretion increased in association with an increase in RBF but AP was unchanged. Isoproterenol 0-13 renin Canis lupus familiaris 92-97 1259022-3 1976 Plasma K concentration was consistently decreased in all three of the above experiments and because hypokalemia is known to increase renin release isoproterenol was not infused intrarenally at the lower rate; the decrease in plasma K level precluded relating the entire response in renin release to isoproterenol. Isoproterenol 147-160 renin Canis lupus familiaris 133-138 4851601-0 1974 Effect of adrenoceptor-blocking agents on the renin response to isoproterenol in dogs. Isoproterenol 64-77 renin Canis lupus familiaris 46-51 5033118-0 1972 Effects of dopamine and isoproterenol on renin secretion in the dog. Isoproterenol 24-37 renin Canis lupus familiaris 41-46 4156186-0 1974 [Action of 3 beta adrenolytics on plasma renin hyperactivity induced by isoprenaline in the anesthtized dog. Isoproterenol 72-84 renin Canis lupus familiaris 41-46 4402350-1 1972 The present study was undertaken to examine whether the beta adrenergic agonist, isoproterenol, increases plasma renin activity (PRA) by activation of intrarenal or extrarenal pathways. Isoproterenol 81-94 renin Canis lupus familiaris 113-118 4402350-18 1972 These results do not provide evidence for a role of intrarenal beta adrenergic receptors in the control of renin release and indicate that the effect of beta adrenergic stimulation with isoproterenol to increase the release of renin is mediated by an extrarenal mechanism. Isoproterenol 186-199 renin Canis lupus familiaris 227-232 4402350-20 1972 isoproterenol occurred in the absence of changes in plasma potassium concentration, renal perfusion pressure, glomerular filtration rate, renal plasma flow, and electrolyte excretion and was not abolished by renal denervation, the possibility must be considered that the effect on renin secretion is mediated by circulatory factors. Isoproterenol 0-13 renin Canis lupus familiaris 281-286 15297251-0 2004 Unequal effects of renin-angiotensin system inhibitors in acute cardiac dysfunction induced by isoproterenol. Isoproterenol 95-108 renin Canis lupus familiaris 19-24 12498925-5 2003 The beta-adrenoceptor agonist isoproterenol (1, 10 and 100 microM) produced a concentration-dependent increase in renin release. Isoproterenol 30-43 renin Canis lupus familiaris 114-119 12498925-6 2003 Pretreatment with W-7 (20 microM) potentiated the stimulation of renin release induced by isoproterenol (1 microM). Isoproterenol 90-103 renin Canis lupus familiaris 65-70