PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11960963-3 2002 Isoproterenol (0.75-24 ng x 100 ml limb volume-1 x min-1) and phenylephrine (0.025-0.8 microg x 100 ml limb volume-1 x min-1) were infused incrementally in the brachial and femoral arteries of 12 normal volunteers; changes in limb blood flow were quantified by using strain-gauge plethysmography. Isoproterenol 0-13 CD59 molecule (CD59 blood group) Homo sapiens 51-56 16973702-9 2006 The increase in HR response to isoproterenol infusion was blunted post-exercise at both 4 and 6 microg kg min-1 (127+/-7 and 132+/-6 beats min-1) compared with pre-exercise (138+/-8 and 141+/-12 beats min-1, P<0.05). Isoproterenol 31-44 CD59 molecule (CD59 blood group) Homo sapiens 106-111 16973702-9 2006 The increase in HR response to isoproterenol infusion was blunted post-exercise at both 4 and 6 microg kg min-1 (127+/-7 and 132+/-6 beats min-1) compared with pre-exercise (138+/-8 and 141+/-12 beats min-1, P<0.05). Isoproterenol 31-44 CD59 molecule (CD59 blood group) Homo sapiens 139-144 16973702-9 2006 The increase in HR response to isoproterenol infusion was blunted post-exercise at both 4 and 6 microg kg min-1 (127+/-7 and 132+/-6 beats min-1) compared with pre-exercise (138+/-8 and 141+/-12 beats min-1, P<0.05). Isoproterenol 31-44 CD59 molecule (CD59 blood group) Homo sapiens 139-144 11960963-3 2002 Isoproterenol (0.75-24 ng x 100 ml limb volume-1 x min-1) and phenylephrine (0.025-0.8 microg x 100 ml limb volume-1 x min-1) were infused incrementally in the brachial and femoral arteries of 12 normal volunteers; changes in limb blood flow were quantified by using strain-gauge plethysmography. Isoproterenol 0-13 CD59 molecule (CD59 blood group) Homo sapiens 119-124 10536644-2 1999 Following administration of atropine, each subject was given an infusion of isoproterenol at incremental doses from 0.010 to 0.030 microgram kg-1 min-1. Isoproterenol 76-89 CD59 molecule (CD59 blood group) Homo sapiens 146-151 9229292-6 1997 isoproterenol: delta P/D 2.07 +/- 1.36 vs 2.18 +/- 1.42 mm Hg/mm; delta Vcfc 1.55 +/- 0.33 vs 1.40 +/- 0.38 square root of min-1 x %/ms), indicating an unchanged inotropic effect mediated by the postsynaptic beta-receptor/effector system. Isoproterenol 0-13 CD59 molecule (CD59 blood group) Homo sapiens 123-128 1980079-5 1990 The maximally isoprenaline-stimulated adenylate cyclase activity rose from 66 +/- 7 to 100 +/- 10 pmol cAMP min-1 mg-1 protein after 15 min of global ischaemia indicating the receptor-mediated sensitization of the beta-adrenergic system. Isoproterenol 14-26 CD59 molecule (CD59 blood group) Homo sapiens 108-118 7893584-8 1994 Metoprolol was given together with the dose of isoprenaline which increased heart rate by 25 beats min-1. Isoproterenol 47-59 CD59 molecule (CD59 blood group) Homo sapiens 99-104 8282375-3 1994 Intravenous infusion of isoproterenol at 0.02 microgram.kg-1 x min-1 for 30 minutes increased mean arterial pressure by 5 mm Hg (P < .05), heart rate by 51 beats per minute (P < .001), and plasma renin activity by 56% (P < .001). Isoproterenol 24-37 CD59 molecule (CD59 blood group) Homo sapiens 63-68 8282375-6 1994 Infusion of isoproterenol at 0.05 microgram.kg-1 x min-1 did not change blood pressure but increased heart rate by 62 beats per minute (P < .001) and plasma renin activity by 283% (P < .001). Isoproterenol 12-25 CD59 molecule (CD59 blood group) Homo sapiens 51-56 1336317-2 1992 The inotropic response induced by isoproterenol (isoprenaline, 20 ng.kg-1 x min-1), measured by m-mode echocardiography as the increase of fractional shortening in seven healthy subjects, was reduced from 17.1 +/- 4.3 to 9.1 +/- 3.9% (P < 0.01) by M-cholinoceptor stimulation using intravenous injection of 3.6 micrograms/kg carbachol. Isoproterenol 34-47 CD59 molecule (CD59 blood group) Homo sapiens 76-81 1336317-2 1992 The inotropic response induced by isoproterenol (isoprenaline, 20 ng.kg-1 x min-1), measured by m-mode echocardiography as the increase of fractional shortening in seven healthy subjects, was reduced from 17.1 +/- 4.3 to 9.1 +/- 3.9% (P < 0.01) by M-cholinoceptor stimulation using intravenous injection of 3.6 micrograms/kg carbachol. Isoproterenol 49-61 CD59 molecule (CD59 blood group) Homo sapiens 76-81 1336317-3 1992 However, the inotropic response of increasing doses of isoprenaline (5-20 ng.kg-1 x min-1) did not differ in 13 healthy subjects without and after M-cholinoceptor blockade (atropine, 0.015 mg/kg i.v. Isoproterenol 55-67 CD59 molecule (CD59 blood group) Homo sapiens 84-89 1336317-4 1992 ); the increase of fractional shortening amounted to 17.4 +/- 4.0 vs. 19.5 +/- 4.8% (NS) in response to 20 ng.kg-1 x min-1 isoprenaline. Isoproterenol 123-135 CD59 molecule (CD59 blood group) Homo sapiens 117-122 8867774-3 1996 Submaximal dynamic exercise and isoprenaline caused the heart rate to rise to 90-114 beats min-1, and increased the ballistocardiographic amplitude threefold, while at the same time shortening the interval between the R-wave of the electrocardiogram and the peak of the ballistocardiographic waveform (P < 0.01). Isoproterenol 32-44 CD59 molecule (CD59 blood group) Homo sapiens 91-96 8527263-6 1995 The dose of isoprenaline required to increase heart rate by 25 beats min-1 (I25) and the dose of phenylephrine required to increase systolic and diastolic blood pressure by 20 mm Hg (PS20 and PD20) were calculated using a quadratic fit to individual dose-response curves. Isoproterenol 12-24 CD59 molecule (CD59 blood group) Homo sapiens 69-74 2570700-2 1989 Following placebo, the dose of isoproterenol which increased the heart rate by 25 beats.min-1 (CD25) was 0.84 (0.1-2.72) micrograms (median and range). Isoproterenol 31-44 CD59 molecule (CD59 blood group) Homo sapiens 88-93 3330526-9 1987 The dose of isoproterenol necessary to induce an increase of heart rate by 20 beats min-1 was after AQ-A 39 4.2 times greater and following propranolol 9.2 times greater than during placebo. Isoproterenol 12-25 CD59 molecule (CD59 blood group) Homo sapiens 84-89 3046824-10 1988 Mean peak plasma isoprenaline levels were 0.16 +/- 0.02 nmol/l during the 5 ng min-1 kg-1 infusion and 0.71 +/- 0.05 nmol/l during the 15 ng min-1 kg-1 infusion. Isoproterenol 17-29 CD59 molecule (CD59 blood group) Homo sapiens 79-84 3026718-2 1987 In vivo, blood pressure, heart rate, plasma noradrenaline and plasma cyclic AMP responses to isoprenaline (0.01, 0.02 and 0.05 microgram min-1 kg-1 intravenously) were related to the plasma concentrations of isoprenaline. Isoproterenol 93-105 CD59 molecule (CD59 blood group) Homo sapiens 137-147 2883988-12 1987 After each dose, graded infusions of isoprenaline were given until the heart rate increased by 50 beats min-1. Isoproterenol 37-49 CD59 molecule (CD59 blood group) Homo sapiens 104-109 2888649-3 1987 We observed no significant difference (p greater than 0.1) between the heat tolerant (0.9 +/- 0.68 microgram) and heat intolerant (1.19 +/- 0.61 microgram) subjects in the dose of isoproterenol that produced a 25 beat.min-1 increment in heart rate. Isoproterenol 180-193 CD59 molecule (CD59 blood group) Homo sapiens 218-223 3026718-2 1987 In vivo, blood pressure, heart rate, plasma noradrenaline and plasma cyclic AMP responses to isoprenaline (0.01, 0.02 and 0.05 microgram min-1 kg-1 intravenously) were related to the plasma concentrations of isoprenaline. Isoproterenol 208-220 CD59 molecule (CD59 blood group) Homo sapiens 137-147 3954935-2 1986 In patients with cirrhosis, the dose of isoprenaline required to increase the resting heart rate by 25 beats min-1 (chronotropic dose 25 or CD25) ranged from 2.50 to 34.73 micrograms (median: 4.47 micrograms) and was significantly higher than in controls (range: 0.66 to 2.76 micrograms, median: 1.34 micrograms). Isoproterenol 40-52 CD59 molecule (CD59 blood group) Homo sapiens 109-114 6291881-6 1982 The Ab+ subjects required 15.0 +/- 1.9 ng isoprenaline (isoproterenol) kg-1 min-1 i.v. Isoproterenol 42-54 CD59 molecule (CD59 blood group) Homo sapiens 76-81 3830711-1 1985 Although anterograde conduction through a Kent bundle with a short refractory period was suppressed by 300 mg of flecainide acetate, the infusion of small amounts of isoproterenol caused the reappearance of WPW and permitted the induction of an atrial tachycardia with 1/1 conduction through the accessory pathway at a rate of 260 beats min-1. Isoproterenol 166-179 CD59 molecule (CD59 blood group) Homo sapiens 337-342 6291881-6 1982 The Ab+ subjects required 15.0 +/- 1.9 ng isoprenaline (isoproterenol) kg-1 min-1 i.v. Isoproterenol 56-69 CD59 molecule (CD59 blood group) Homo sapiens 76-81 33536-4 1979 Injections of small doses (0.02 to 0.4 microg kg-1 min-1) of isoprenaline induced the same pattern of changes in the FECG as we have previously recorded during hypoxia. Isoproterenol 61-73 CD59 molecule (CD59 blood group) Homo sapiens 51-56 653312-2 1978 infusions of isoprenaline in a dose of 0.03 microgram x kg-1 x min-1 over a period of 6 min. Isoproterenol 13-25 CD59 molecule (CD59 blood group) Homo sapiens 63-68 741096-5 1978 DOPA and isoprenaline increased cardiac index by an average of 1.01 and 0.94 1 min--1 m--2; noradrenaline did not significantly improve peripheral perfusion. Isoproterenol 9-21 CD59 molecule (CD59 blood group) Homo sapiens 79-85 24364280-6 2013 After placement of transcutaneous cardiac pacing pads on the chest, we administered isoproterenol at 0.01 microg x kg(-1) x min(-1). Isoproterenol 84-97 CD59 molecule (CD59 blood group) Homo sapiens 124-130 24364280-7 2013 We confirmed an increase in HR to 50 beats x min(-1) and induced anesthesia, after which isoproterenol was administered at 0.015 microg x kg(-1) x min(-1). Isoproterenol 89-102 CD59 molecule (CD59 blood group) Homo sapiens 147-153