PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11330331-2	2001	ET-1 (8 nM) was applied in three experimental arrangements: untreated cells, in the presence of 50 nM isoproterenol, and in the presence of 250 microM 8-bromo-cAMP.	Isoproterenol	102-115	endothelin 1	Canis lupus familiaris	0-4	
15158364-12	2004	Isoproterenol treatment showed antagonistic effect against endothelin-1 induced MAP duration prolongation, early after depolarisation and ventricular fibrillation formation, while endothelin-1 showed protective effect against the development of isoproterenol induced atrial fibrillation.	Isoproterenol	0-13	endothelin 1	Canis lupus familiaris	59-71	
15158364-12	2004	Isoproterenol treatment showed antagonistic effect against endothelin-1 induced MAP duration prolongation, early after depolarisation and ventricular fibrillation formation, while endothelin-1 showed protective effect against the development of isoproterenol induced atrial fibrillation.	Isoproterenol	245-258	endothelin 1	Canis lupus familiaris	180-192	
11330331-8	2001	ET-1 reduced ICa also in isoproterenol-treated cells by 17.8+/-2% (P<0.05); this inhibition was significantly less than obtained in untreated cells.	Isoproterenol	25-38	endothelin 1	Canis lupus familiaris	0-4	
11330331-10	2001	This effect of isoproterenol on IK was reduced by 31.8+/-4.8% if the cells were pretreated with ET-1.	Isoproterenol	15-28	endothelin 1	Canis lupus familiaris	96-100	
11330331-11	2001	Similarly, in isoproterenol-treated cells ET-1 decreased IK by 16.2+/-1.5% (P<0.05).	Isoproterenol	14-27	endothelin 1	Canis lupus familiaris	42-46	
10975592-2	2000	ET-1 (10(-8) M) had no effect on the baseline I(Ca), but at 10(-9)-10(-7) M, it inhibited the isoproterenol (ISO)-induced increase in I(Ca).	Isoproterenol	94-107	endothelin 1	Canis lupus familiaris	0-4