PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 918855-1 1977 The effect of isoproterenol on pancreatic secretion stimulated by the octapeptide of cholecystokinin (OP-CCK) was studied in dogs with gastric and pancreatic fistulas. Isoproterenol 14-27 cholecystokinin Canis lupus familiaris 85-108 918855-4 1977 Isoproterenol inhibited these pancreatic responses to OP-CCK, and the degree of inhibition was dose related. Isoproterenol 0-13 cholecystokinin Canis lupus familiaris 57-60 918855-7 1977 The experiments show that isoproterenol inhibits OP-CCK--stimulated pancreatic secretion by a beta-adrenergic mechanism. Isoproterenol 26-39 cholecystokinin Canis lupus familiaris 52-55 2475982-3 1989 Pancreatic blood flow remained unaffected by the action of isoproterenol; however, the administration of the beta-adrenergic agonist over an infusion of secretion an OP-CCK led to an increase in pancreatic juice flow (approximately 146% for secretin and 125% for OP-CCK) and HCO3-output (approximately 194% for secretin and 150% for OP-CCK), a potentiation being observed between the effects of secretin and isoproterenol. Isoproterenol 59-72 cholecystokinin Canis lupus familiaris 169-172 2475982-3 1989 Pancreatic blood flow remained unaffected by the action of isoproterenol; however, the administration of the beta-adrenergic agonist over an infusion of secretion an OP-CCK led to an increase in pancreatic juice flow (approximately 146% for secretin and 125% for OP-CCK) and HCO3-output (approximately 194% for secretin and 150% for OP-CCK), a potentiation being observed between the effects of secretin and isoproterenol. Isoproterenol 408-421 cholecystokinin Canis lupus familiaris 169-172 2475982-5 1989 Isoproterenol interferes with the action of secretin and OP-CCK in that it partially inhibits the stimulatory action of OP-CCK on the enzymatic secretion of the acinar cells in the rabbit pancreas and at the same time protein secretion decreases in the presence of secretin. Isoproterenol 0-13 cholecystokinin Canis lupus familiaris 123-126