PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16509761-1 2006 BACKGROUND: Ruboxistaurin, a specific inhibitor of the beta(1) and beta(2) isoforms of protein kinase C, is currently in clinical development for the treatment of several diabetic microvascular complications. ruboxistaurin 12-25 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 67-74 10470381-1 1999 The macrocyclic bisindolylmaleimide, LY333531, selectively inhibits protein kinase C beta 1 and beta 2 isoforms with an approximate IC50 of 5 nanomolar. ruboxistaurin 37-45 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 96-102