PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12167476-9	2002	In addition, curcumin inhibited verapamil-stimulated ATPase activity and the photoaffinity labeling of Pgp with the prazosin analog [125I]iodoarylazidoprazosin in a concentration-dependent manner, demonstrating that curcumin interacts directly with the transporter.	Prazosin	116-124	ATP binding cassette subfamily B member 1	Homo sapiens	103-106	
16489767-6	2006	However, the ability of Pgp substrates (such as prazosin) to stimulate ATP hydrolysis and facilitate vanadate-induced trapping of [alpha-(32)P]-8-azido-ADP is substantially affected in the presence of cis-(Z)-flupentixol.	Prazosin	48-56	ATP binding cassette subfamily B member 1	Homo sapiens	24-27	
10092872-0	1999	Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone.	Prazosin	57-65	ATP binding cassette subfamily B member 1	Homo sapiens	15-29	
7547962-7	1995	P-glycoprotein modulators generally demonstrated significantly greater potency (EC50; microM): SDZ PSC 833, 0.08; cyclosporin A, 1.3; verapamil, 4.1; quinidine, 6.4; prazosin, > 300.	Prazosin	166-174	ATP binding cassette subfamily B member 1	Homo sapiens	0-14	
20423956-8	2010	Finally, we found that all TKIs were able to compete labeling of ABCB1 and ABCG2 by the photo-cross-linkable prazosin analog [(125)I]iodoarylazidoprazosin, suggesting interaction at the prazosin-binding site of both proteins.	Prazosin	109-117	ATP binding cassette subfamily B member 1	Homo sapiens	65-70	
20423956-8	2010	Finally, we found that all TKIs were able to compete labeling of ABCB1 and ABCG2 by the photo-cross-linkable prazosin analog [(125)I]iodoarylazidoprazosin, suggesting interaction at the prazosin-binding site of both proteins.	Prazosin	146-154	ATP binding cassette subfamily B member 1	Homo sapiens	65-70	
9380680-5	1997	In this study, using [125I]iodoarylazidoprazosin ([125I]IAAP), a photoactive analog of prazosin, we have demonstrated the presence of two nonidentical drug-interaction sites within Pgp.	Prazosin	40-48	ATP binding cassette subfamily B member 1	Homo sapiens	181-184	
22004608-9	2011	Ko143-sensitive transepithelial secretion of the bi-substrate (MDR1/BCRP) prazosin was also increased in the presence of rosiglitazone.	Prazosin	74-82	ATP binding cassette subfamily B member 1	Homo sapiens	63-67	
19380024-4	2009	The mRNA expression of the ABCB1 gene (previously MDR1) in human colon carcinoma HT-29 cell line was measured after treatment with an adrenergic receptor agonist (adrenaline) and various antagonists (propranolol, prazosin, and yohimbine).	Prazosin	213-221	ATP binding cassette subfamily B member 1	Homo sapiens	27-32	
19380024-4	2009	The mRNA expression of the ABCB1 gene (previously MDR1) in human colon carcinoma HT-29 cell line was measured after treatment with an adrenergic receptor agonist (adrenaline) and various antagonists (propranolol, prazosin, and yohimbine).	Prazosin	213-221	ATP binding cassette subfamily B member 1	Homo sapiens	50-54	
14979722-4	2004	The stipiamide homodimers displaced [(125)I]iodoarylazidoprazoin (IAAP), an analogue of the Pgp substrate prazosin.	Prazosin	106-114	ATP binding cassette subfamily B member 1	Homo sapiens	92-95