PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1681068-3 1991 In the presence of AAG the EC50 value of phenylephrine at 5.69 nM unbound prazosin was on average 47% lower than in the absence of AAG (P less than 0.002), at 122 nM unbound tiodazosin, 39% lower (P less than 0.01), and at 25.6 nM unbound WB4101, 68% lower (P less than 0.002). Prazosin 74-82 alpha-1-acid glycoprotein Oryctolagus cuniculus 19-22 1681068-6 1991 The effect of AAG on the antagonistic activity of prazosin was concentration-dependent with a maximum suppression of prazosin activity of 79% and with a half-maximum concentration of 1.1 microM AAG. Prazosin 50-58 alpha-1-acid glycoprotein Oryctolagus cuniculus 14-17 1681068-6 1991 The effect of AAG on the antagonistic activity of prazosin was concentration-dependent with a maximum suppression of prazosin activity of 79% and with a half-maximum concentration of 1.1 microM AAG. Prazosin 50-58 alpha-1-acid glycoprotein Oryctolagus cuniculus 194-197 1681068-6 1991 The effect of AAG on the antagonistic activity of prazosin was concentration-dependent with a maximum suppression of prazosin activity of 79% and with a half-maximum concentration of 1.1 microM AAG. Prazosin 117-125 alpha-1-acid glycoprotein Oryctolagus cuniculus 14-17 1681068-7 1991 AAG significantly decreased prazosin"s ability to reduce alpha 1-adrenergic stimulation of calcium influx (P less than 0.05), while it had no effect on prazosin"s ability to decrease alpha 1-adrenergic-stimulated formation of inositol phosphate. Prazosin 28-36 alpha-1-acid glycoprotein Oryctolagus cuniculus 0-3